Slusher BS - Search Results

1

Enantiospecificity of glutamate carboxypeptidase II inhibition.

Tsukamoto T, Majer P, Vitharana D, Ni C, Hin B, Lu XC, Thomas AG, Wozniak KM, Calvin DC, Wu Y, Slusher BS, Scarpetti D, Bonneville GW. Tsukamoto T, et al. Among authors: slusher bs. J Med Chem. 2005 Apr 7;48(7):2319-24. doi: 10.1021/jm049258g. J Med Chem. 2005. PMID: 15801825

2

Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated alpha-linked acidic dipeptidase.

Jackson PF, Cole DC, Slusher BS, Stetz SL, Ross LE, Donzanti BA, Trainor DA. Jackson PF, et al. Among authors: slusher bs. J Med Chem. 1996 Jan 19;39(2):619-22. doi: 10.1021/jm950801q. J Med Chem. 1996. PMID: 8558536

3

Characterization of the enzymatic activity of PSM: comparison with brain NAALADase.

Tiffany CW, Lapidus RG, Merion A, Calvin DC, Slusher BS. Tiffany CW, et al. Among authors: slusher bs. Prostate. 1999 Apr 1;39(1):28-35. doi: 10.1002/(sici)1097-0045(19990401)39:1<28::aid-pros5>3.0.co;2-a. Prostate. 1999. PMID: 10221263

4

Toxicity induced by a polyglutamated folate analog is attenuated by NAALADase inhibition.

Thomas AG, Olkowski JL, Vornov JJ, Slusher BS. Thomas AG, et al. Among authors: slusher bs. Brain Res. 1999 Oct 2;843(1-2):48-52. doi: 10.1016/s0006-8993(99)01879-x. Brain Res. 1999. PMID: 10528109

5

Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury.

Slusher BS, Vornov JJ, Thomas AG, Hurn PD, Harukuni I, Bhardwaj A, Traystman RJ, Robinson MB, Britton P, Lu XC, Tortella FC, Wozniak KM, Yudkoff M, Potter BM, Jackson PF. Slusher BS, et al. Nat Med. 1999 Dec;5(12):1396-402. doi: 10.1038/70971. Nat Med. 1999. PMID: 10581082

6

Blockade of NAALADase: a novel neuroprotective strategy based on limiting glutamate and elevating NAAG.

Vornov JJ, Wozniak K, Lu M, Jackson P, Tsukamoto T, Wang E, Slusher B. Vornov JJ, et al. Ann N Y Acad Sci. 1999;890:400-5. doi: 10.1111/j.1749-6632.1999.tb08019.x. Ann N Y Acad Sci. 1999. PMID: 10668445

7

N-Acetylated alpha-linked acidic dipeptidase converts N-acetylaspartylglutamate from a neuroprotectant to a neurotoxin.

Thomas AG, Vornov JJ, Olkowski JL, Merion AT, Slusher BS. Thomas AG, et al. Among authors: slusher bs. J Pharmacol Exp Ther. 2000 Oct;295(1):16-22. J Pharmacol Exp Ther. 2000. PMID: 10991955

8

Expression and acquisition of the conditioned place preference response to cocaine in rats is blocked by selective inhibitors of the enzyme N-acetylated-alpha-linked-acidic dipeptidase (NAALADASE).

Slusher BS, Thomas A, Paul M, Schad CA, Ashby CR Jr. Slusher BS, et al. Synapse. 2001 Jul;41(1):22-8. doi: 10.1002/syn.1056. Synapse. 2001. PMID: 11354010

9

Design of NAALADase inhibitors: a novel neuroprotective strategy.

Jackson PF, Slusher BS. Jackson PF, et al. Among authors: slusher bs. Curr Med Chem. 2001 Jul;8(8):949-57. doi: 10.2174/0929867013372797. Curr Med Chem. 2001. PMID: 11375762

10

Neuroprotection afforded by NAAG and NAALADase inhibition requires glial cells and metabotropic glutamate receptor activation.

Thomas AG, Olkowski JL, Slusher BS. Thomas AG, et al. Among authors: slusher bs. Eur J Pharmacol. 2001 Aug 24;426(1-2):35-8. doi: 10.1016/s0014-2999(01)01198-0. Eur J Pharmacol. 2001. PMID: 11525768

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