Fan Z - Search Results

1

The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression.

Luwor RB, Lu Y, Li X, Mendelsohn J, Fan Z. Luwor RB, et al. Among authors: fan z. Oncogene. 2005 Jun 23;24(27):4433-41. doi: 10.1038/sj.onc.1208625. Oncogene. 2005. PMID: 15806152

2

Epidermal growth factor receptor (EGFR) ubiquitination as a mechanism of acquired resistance escaping treatment by the anti-EGFR monoclonal antibody cetuximab.

Lu Y, Li X, Liang K, Luwor R, Siddik ZH, Mills GB, Mendelsohn J, Fan Z. Lu Y, et al. Among authors: fan z. Cancer Res. 2007 Sep 1;67(17):8240-7. doi: 10.1158/0008-5472.CAN-07-0589. Cancer Res. 2007. PMID: 17804738

3

Responses of cancer cells with wild-type or tyrosine kinase domain-mutated epidermal growth factor receptor (EGFR) to EGFR-targeted therapy are linked to downregulation of hypoxia-inducible factor-1alpha.

Lu Y, Liang K, Li X, Fan Z. Lu Y, et al. Among authors: fan z. Mol Cancer. 2007 Oct 11;6:63. doi: 10.1186/1476-4598-6-63. Mol Cancer. 2007. PMID: 17931419 Free PMC article.

4

Requirement of hypoxia-inducible factor-1alpha down-regulation in mediating the antitumor activity of the anti-epidermal growth factor receptor monoclonal antibody cetuximab.

Li X, Lu Y, Liang K, Pan T, Mendelsohn J, Fan Z. Li X, et al. Among authors: fan z. Mol Cancer Ther. 2008 May;7(5):1207-17. doi: 10.1158/1535-7163.MCT-07-2187. Mol Cancer Ther. 2008. PMID: 18483308

5

The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1alpha and Bcl-2 and activating the beclin 1/hVps34 complex.

Li X, Fan Z. Li X, et al. Among authors: fan z. Cancer Res. 2010 Jul 15;70(14):5942-52. doi: 10.1158/0008-5472.CAN-10-0157. Cancer Res. 2010. PMID: 20634405 Free PMC article.

6

Roles of autophagy in cetuximab-mediated cancer therapy against EGFR.

Li X, Lu Y, Pan T, Fan Z. Li X, et al. Among authors: fan z. Autophagy. 2010 Nov;6(8):1066-77. doi: 10.4161/auto.6.8.13366. Autophagy. 2010. PMID: 20864811 Free PMC article.

7

1, 9-Pyrazoloanthrones downregulate HIF-1α and sensitize cancer cells to cetuximab-mediated anti-EGFR therapy.

Lu Y, Li X, Lu H, Fan Z. Lu Y, et al. Among authors: fan z. PLoS One. 2010 Dec 29;5(12):e15823. doi: 10.1371/journal.pone.0015823. PLoS One. 2010. PMID: 21209911 Free PMC article.

8

Constitutively active Harvey Ras confers resistance to epidermal growth factor receptor-targeted therapy with cetuximab and gefitinib.

Luwor RB, Lu Y, Li X, Liang K, Fan Z. Luwor RB, et al. Among authors: fan z. Cancer Lett. 2011 Jul 1;306(1):85-91. doi: 10.1016/j.canlet.2011.02.035. Epub 2011 Mar 15. Cancer Lett. 2011. PMID: 21411223 Free PMC article.

9

HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.

Knuefermann C, Lu Y, Liu B, Jin W, Liang K, Wu L, Schmidt M, Mills GB, Mendelsohn J, Fan Z. Knuefermann C, et al. Among authors: fan z. Oncogene. 2003 May 22;22(21):3205-12. doi: 10.1038/sj.onc.1206394. Oncogene. 2003. PMID: 12761490

10

Sensitization of breast cancer cells to radiation by trastuzumab.

Liang K, Lu Y, Jin W, Ang KK, Milas L, Fan Z. Liang K, et al. Among authors: fan z. Mol Cancer Ther. 2003 Nov;2(11):1113-20. Mol Cancer Ther. 2003. PMID: 14617784

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