Hackett JC - Search Results

1

Aromatase inhibitors in the treatment of breast cancer.

Brueggemeier RW, Hackett JC, Diaz-Cruz ES. Brueggemeier RW, et al. Among authors: hackett jc. Endocr Rev. 2005 May;26(3):331-45. doi: 10.1210/er.2004-0015. Epub 2005 Apr 6. Endocr Rev. 2005. PMID: 15814851 Review.

2

Synthesis and aromatase inhibitory activity of novel pyridine-containing isoflavones.

Kim YW, Hackett JC, Brueggemeier RW. Kim YW, et al. Among authors: hackett jc. J Med Chem. 2004 Jul 29;47(16):4032-40. doi: 10.1021/jm0306024. J Med Chem. 2004. PMID: 15267241

3

Synthesis and characterization of azole isoflavone inhibitors of aromatase.

Hackett JC, Kim YW, Su B, Brueggemeier RW. Hackett JC, et al. Bioorg Med Chem. 2005 Jun 2;13(12):4063-70. doi: 10.1016/j.bmc.2005.03.050. Epub 2005 Apr 25. Bioorg Med Chem. 2005. PMID: 15911319

4

Lead optimization of 7-benzyloxy 2-(4'-pyridylmethyl)thio isoflavone aromatase inhibitors.

Su B, Hackett JC, Díaz-Cruz ES, Kim YW, Brueggemeier RW. Su B, et al. Among authors: hackett jc. Bioorg Med Chem. 2005 Dec 1;13(23):6571-7. doi: 10.1016/j.bmc.2005.07.038. Epub 2005 Aug 24. Bioorg Med Chem. 2005. PMID: 16125392

5

Development of keratinocyte growth factor receptor tyrosine kinase inhibitors for the treatment of cancer.

Hackett J, Xiao Z, Zang XP, Lerner ML, Brackett DJ, Brueggemeier RW, Li PK, Pento JT. Hackett J, et al. Anticancer Res. 2007 Nov-Dec;27(6B):3801-6. Anticancer Res. 2007. PMID: 18225535 Free article.

6

The final catalytic step of cytochrome p450 aromatase: a density functional theory study.

Hackett JC, Brueggemeier RW, Hadad CM. Hackett JC, et al. J Am Chem Soc. 2005 Apr 13;127(14):5224-37. doi: 10.1021/ja044716w. J Am Chem Soc. 2005. PMID: 15810858

7

Evidence for an elevated aspartate pK(a) in the active site of human aromatase.

Di Nardo G, Breitner M, Bandino A, Ghosh D, Jennings GK, Hackett JC, Gilardi G. Di Nardo G, et al. Among authors: hackett jc. J Biol Chem. 2015 Jan 9;290(2):1186-96. doi: 10.1074/jbc.M114.595108. Epub 2014 Nov 25. J Biol Chem. 2015. PMID: 25425647 Free PMC article.

8

Oxidative dehalogenation of perhalogenated benzenes by cytochrome P450 compound I.

Hackett JC, Sanan TT, Hadad CM. Hackett JC, et al. Biochemistry. 2007 May 22;46(20):5924-40. doi: 10.1021/bi700365x. Epub 2007 Apr 25. Biochemistry. 2007. PMID: 17455915

9

The direct detection of an aryl azide excited state: an ultrafast study of the photochemistry of para- and ortho-biphenyl azide.

Burdzinski GT, Gustafson TL, Hackett JC, Hadad CM, Platz MS. Burdzinski GT, et al. Among authors: hackett jc. J Am Chem Soc. 2005 Oct 12;127(40):13764-5. doi: 10.1021/ja054135m. J Am Chem Soc. 2005. PMID: 16201777

10

Early events in the photochemistry of aryl azides from femtosecond UV/Vis spectroscopy and quantum chemical calculations.

Burdzinski G, Hackett JC, Wang J, Gustafson TL, Hadad CM, Platz MS. Burdzinski G, et al. Among authors: hackett jc. J Am Chem Soc. 2006 Oct 18;128(41):13402-11. doi: 10.1021/ja061520i. J Am Chem Soc. 2006. PMID: 17031952

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