Lu H - Search Results

1

Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41.

Liu S, Lu H, Zhao Q, He Y, Niu J, Debnath AK, Wu S, Jiang S. Liu S, et al. Among authors: lu h. Biochim Biophys Acta. 2005 May 25;1723(1-3):270-81. doi: 10.1016/j.bbagen.2005.02.012. Epub 2005 Mar 24. Biochim Biophys Acta. 2005. PMID: 15823507

2

Conserved salt bridge between the N- and C-terminal heptad repeat regions of the human immunodeficiency virus type 1 gp41 core structure is critical for virus entry and inhibition.

He Y, Liu S, Li J, Lu H, Qi Z, Liu Z, Debnath AK, Jiang S. He Y, et al. Among authors: lu h. J Virol. 2008 Nov;82(22):11129-39. doi: 10.1128/JVI.01060-08. Epub 2008 Sep 3. J Virol. 2008. PMID: 18768964 Free PMC article.

3

Design, synthesis, and biological activity of novel 5-((arylfuran/1H-pyrrol-2-yl)methylene)-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-4-ones as HIV-1 fusion inhibitors targeting gp41.

Jiang S, Tala SR, Lu H, Abo-Dya NE, Avan I, Gyanda K, Lu L, Katritzky AR, Debnath AK. Jiang S, et al. Among authors: lu h, lu l. J Med Chem. 2011 Jan 27;54(2):572-9. doi: 10.1021/jm101014v. Epub 2010 Dec 29. J Med Chem. 2011. PMID: 21190369

4

Design, synthesis, and biological activity of a novel series of 2,5-disubstituted furans/pyrroles as HIV-1 fusion inhibitors targeting gp41.

Jiang S, Tala SR, Lu H, Zou P, Avan I, Ibrahim TS, Abo-Dya NE, Abdelmajeid A, Debnath AK, Katritzky AR. Jiang S, et al. Among authors: lu h. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6895-8. doi: 10.1016/j.bmcl.2011.08.081. Epub 2011 Sep 5. Bioorg Med Chem Lett. 2011. PMID: 21978673

5

Automatic quantitation of HIV-1 mediated cell-to-cell fusion with a digital image analysis system (DIAS): application for rapid screening of HIV-1 fusion inhibitors.

Lu H, Zhao Q, Xu Z, Jiang S. Lu H, et al. J Virol Methods. 2003 Feb;107(2):155-61. doi: 10.1016/s0166-0934(02)00213-6. J Virol Methods. 2003. PMID: 12505629

6

Development of a cell-based enzyme-linked immunosorbent assay for high-throughput screening of HIV type 1 entry inhibitors targeting the coreceptor CXCR4.

Zhao Q, Lu H, Schols D, De Clercq E, Jiang S. Zhao Q, et al. Among authors: lu h. AIDS Res Hum Retroviruses. 2003 Nov;19(11):947-55. doi: 10.1089/088922203322588297. AIDS Res Hum Retroviruses. 2003. PMID: 14678601

7

Rapid and automated fluorescence-linked immunosorbent assay for high-throughput screening of HIV-1 fusion inhibitors targeting gp41.

Liu S, Boyer-Chatenet L, Lu H, Jiang S. Liu S, et al. Among authors: lu h. J Biomol Screen. 2003 Dec;8(6):685-93. doi: 10.1177/1087057103259155. J Biomol Screen. 2003. PMID: 14711394

8

N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion.

Jiang S, Lu H, Liu S, Zhao Q, He Y, Debnath AK. Jiang S, et al. Among authors: lu h. Antimicrob Agents Chemother. 2004 Nov;48(11):4349-59. doi: 10.1128/AAC.48.11.4349-4359.2004. Antimicrob Agents Chemother. 2004. PMID: 15504864 Free PMC article.

9

Different from the HIV fusion inhibitor C34, the anti-HIV drug Fuzeon (T-20) inhibits HIV-1 entry by targeting multiple sites in gp41 and gp120.

Liu S, Lu H, Niu J, Xu Y, Wu S, Jiang S. Liu S, et al. Among authors: lu h. J Biol Chem. 2005 Mar 25;280(12):11259-73. doi: 10.1074/jbc.M411141200. Epub 2005 Jan 7. J Biol Chem. 2005. PMID: 15640162 Free article.

10

Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4.

Zhao Q, Ma L, Jiang S, Lu H, Liu S, He Y, Strick N, Neamati N, Debnath AK. Zhao Q, et al. Among authors: lu h. Virology. 2005 Sep 1;339(2):213-25. doi: 10.1016/j.virol.2005.06.008. Virology. 2005. PMID: 15996703 Free article.

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