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Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes involved in stem-cell maintenance.
Alcalay M, Tiacci E, Bergomas R, Bigerna B, Venturini E, Minardi SP, Meani N, Diverio D, Bernard L, Tizzoni L, Volorio S, Luzi L, Colombo E, Lo Coco F, Mecucci C, Falini B, Pelicci PG. Alcalay M, et al. Blood. 2005 Aug 1;106(3):899-902. doi: 10.1182/blood-2005-02-0560. Epub 2005 Apr 14. Blood. 2005. PMID: 15831697 Free article.
Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.
Pandolfi PP, Alcalay M, Fagioli M, Zangrilli D, Mencarelli A, Diverio D, Biondi A, Lo Coco F, Rambaldi A, Grignani F, et al. Pandolfi PP, et al. Among authors: alcalay m. EMBO J. 1992 Apr;11(4):1397-407. doi: 10.1002/j.1460-2075.1992.tb05185.x. EMBO J. 1992. PMID: 1314166 Free PMC article.
237 results