Das P - Search Results

1

Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Abeta42 production.

Kukar T, Murphy MP, Eriksen JL, Sagi SA, Weggen S, Smith TE, Ladd T, Khan MA, Kache R, Beard J, Dodson M, Merit S, Ozols VV, Anastasiadis PZ, Das P, Fauq A, Koo EH, Golde TE. Kukar T, et al. Among authors: das p. Nat Med. 2005 May;11(5):545-50. doi: 10.1038/nm1235. Epub 2005 Apr 17. Nat Med. 2005. PMID: 15834426

2

Overexpression of nicastrin increases Abeta production.

Murphy MP, Das P, Nyborg AC, Rochette MJ, Dodson MW, Loosbrock NM, Souder TM, McLendon C, Merit SL, Piper SC, Jansen KR, Golde TE. Murphy MP, et al. Among authors: das p. FASEB J. 2003 Jun;17(9):1138-40. doi: 10.1096/fj.02-1050fje. Epub 2003 Apr 8. FASEB J. 2003. PMID: 12692078

3

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo.

Eriksen JL, Sagi SA, Smith TE, Weggen S, Das P, McLendon DC, Ozols VV, Jessing KW, Zavitz KH, Koo EH, Golde TE. Eriksen JL, et al. Among authors: das p. J Clin Invest. 2003 Aug;112(3):440-9. doi: 10.1172/JCI18162. J Clin Invest. 2003. PMID: 12897211 Free PMC article.

4

Dysfunction of TGF-beta signaling in Alzheimer's disease.

Das P, Golde T. Das P, et al. J Clin Invest. 2006 Nov;116(11):2855-7. doi: 10.1172/JCI30284. J Clin Invest. 2006. PMID: 17080189 Free PMC article.

5

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.

Weggen S, Eriksen JL, Das P, Sagi SA, Wang R, Pietrzik CU, Findlay KA, Smith TE, Murphy MP, Bulter T, Kang DE, Marquez-Sterling N, Golde TE, Koo EH. Weggen S, et al. Among authors: das p. Nature. 2001 Nov 8;414(6860):212-6. doi: 10.1038/35102591. Nature. 2001. PMID: 11700559

6

Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains.

Wahrle S, Das P, Nyborg AC, McLendon C, Shoji M, Kawarabayashi T, Younkin LH, Younkin SG, Golde TE. Wahrle S, et al. Among authors: das p. Neurobiol Dis. 2002 Feb;9(1):11-23. doi: 10.1006/nbdi.2001.0470. Neurobiol Dis. 2002. PMID: 11848681

7

Open peer commentary regarding Abeta immunization and CNS inflammation by Pasinetti et al.

Das P, Golde TE. Das P, et al. Neurobiol Aging. 2002 Sep-Oct;23(5):671-4; discussion 683-4. doi: 10.1016/s0197-4580(02)00031-3. Neurobiol Aging. 2002. PMID: 12392769 Review. No abstract available.

8

Abeta42 is essential for parenchymal and vascular amyloid deposition in mice.

McGowan E, Pickford F, Kim J, Onstead L, Eriksen J, Yu C, Skipper L, Murphy MP, Beard J, Das P, Jansen K, DeLucia M, Lin WL, Dolios G, Wang R, Eckman CB, Dickson DW, Hutton M, Hardy J, Golde T. McGowan E, et al. Among authors: das p. Neuron. 2005 Jul 21;47(2):191-199. doi: 10.1016/j.neuron.2005.06.030. Neuron. 2005. PMID: 16039562 Free PMC article.

9

Anti-Abeta42- and anti-Abeta40-specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model.

Levites Y, Das P, Price RW, Rochette MJ, Kostura LA, McGowan EM, Murphy MP, Golde TE. Levites Y, et al. Among authors: das p. J Clin Invest. 2006 Jan;116(1):193-201. doi: 10.1172/JCI25410. Epub 2005 Dec 8. J Clin Invest. 2006. PMID: 16341263 Free PMC article.

10

Quantitative and mechanistic studies of Abeta immunotherapy.

Golde TE, Das P, Levites Y. Golde TE, et al. Among authors: das p. CNS Neurol Disord Drug Targets. 2009 Mar;8(1):31-49. doi: 10.2174/187152709787601830. CNS Neurol Disord Drug Targets. 2009. PMID: 19275635 Review.

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