Mohan R - Search Results

1

Solid-phase synthesis of naphthylamidines as factor VIIa/tissue factor inhibitors.

Buckman BO, Chou YL, McCarrick M, Liang A, Lentz D, Mohan R, Morrissey MM, Shaw KJ, Trinh L, Light DR. Buckman BO, et al. Among authors: mohan r. Bioorg Med Chem Lett. 2005 May 2;15(9):2249-52. doi: 10.1016/j.bmcl.2005.03.019. Bioorg Med Chem Lett. 2005. PMID: 15837303

2

Design, synthesis, and biological activity of novel factor Xa inhibitors: 4-aryloxy substituents of 2,6-diphenoxypyridines.

Ng HP, Buckman BO, Eagen KA, Guilford WJ, Kochanny MJ, Mohan R, Shaw KJ, Wu SC, Lentz D, Liang A, Trinh L, Ho E, Smith D, Subramanyam B, Vergona R, Walters J, White KA, Sullivan ME, Morrissey MM, Phillips GB. Ng HP, et al. Among authors: mohan r. Bioorg Med Chem. 2002 Mar;10(3):657-66. doi: 10.1016/s0968-0896(01)00338-8. Bioorg Med Chem. 2002. PMID: 11814853

3

Design, synthesis, and activity of a novel series of factor Xa inhibitors: optimization of arylamidine groups.

Phillips G, Guilford WJ, Buckman BO, Davey DD, Eagen KA, Koovakkat S, Liang A, McCarrick M, Mohan R, Ng HP, Pinkerton M, Subramanyam B, Ho E, Trinh L, Whitlow M, Wu S, Xu W, Morrissey MM. Phillips G, et al. Among authors: mohan r. J Med Chem. 2002 Jun 6;45(12):2484-93. doi: 10.1021/jm0200660. J Med Chem. 2002. PMID: 12036356

4

3-Mercaptopropionic acids as efficacious inhibitors of activated thrombin activatable fibrinolysis inhibitor (TAFIa).

Islam I, Bryant J, May K, Mohan R, Yuan S, Kent L, Morser J, Zhao L, Vergona R, White K, Adler M, Whitlow M, Buckman BO. Islam I, et al. Among authors: mohan r. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1349-54. doi: 10.1016/j.bmcl.2006.11.078. Epub 2006 Dec 3. Bioorg Med Chem Lett. 2007. PMID: 17189688

5

Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3, 5-difluoro-6-[3-(4, 5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylgl y cine (ZK-807834): a potent, selective, and orally active inhibitor of the blood coagulation enzyme factor Xa.

Phillips GB, Buckman BO, Davey DD, Eagen KA, Guilford WJ, Hinchman J, Ho E, Koovakkat S, Liang A, Light DR, Mohan R, Ng HP, Post JM, Shaw KJ, Smith D, Subramanyam B, Sullivan ME, Trinh L, Vergona R, Walters J, White K, Whitlow M, Wu S, Xu W, Morrissey MM. Phillips GB, et al. Among authors: mohan r. J Med Chem. 1998 Sep 10;41(19):3557-62. doi: 10.1021/jm980280h. J Med Chem. 1998. PMID: 9733480 No abstract available.

6

Polymer supported bases in solution-phase synthesis. 2. A convenient method for N-alkylation reactions of weakly acidic heterocycles.

Xu W, Mohan R, Morrissey MM. Xu W, et al. Among authors: mohan r. Bioorg Med Chem Lett. 1998 May 5;8(9):1089-92. doi: 10.1016/s0960-894x(98)00173-5. Bioorg Med Chem Lett. 1998. PMID: 9871713

7

Solid-phase synthesis of N-substituted amidinophenoxy pyridines as factor XA inhibitors.

Mohan R, Yun W, Buckman BO, Liang A, Trinh L, Morrissey MM. Mohan R, et al. Bioorg Med Chem Lett. 1998 Jul 21;8(14):1877-82. doi: 10.1016/s0960-894x(98)00333-3. Bioorg Med Chem Lett. 1998. PMID: 9873451

8

Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors.

Buckman BO, Mohan R, Koovakkat S, Liang A, Trinh L, Morrissey MM. Buckman BO, et al. Among authors: mohan r. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2235-40. doi: 10.1016/s0960-894x(98)00386-2. Bioorg Med Chem Lett. 1998. PMID: 9873520

9

Automated parallel solid-phase synthesis of non-peptide CCR1 receptor antagonists.

Buckman BO, Ghannam A, Angela L, Liang M, Mohan R, Ng HP. Buckman BO, et al. Among authors: mohan r. Comb Chem High Throughput Screen. 2002 May;5(3):249-51. doi: 10.2174/1386207024607284. Comb Chem High Throughput Screen. 2002. PMID: 11966433

10

Reversible, orally available ADP receptor (P2Y₁₂) antagonists Part I: Hit to lead process.

Islam I, Yuan S, Wei RG, Xu W, Morrissey M, Mohan R, Zheng D, DiMella A, Dunning L, Snider M, Subramanyam B, Tseng JL, Bryant JA, Buckman BO. Islam I, et al. Among authors: mohan r. Bioorg Med Chem Lett. 2018 May 15;28(9):1459-1463. doi: 10.1016/j.bmcl.2018.03.090. Epub 2018 Mar 31. Bioorg Med Chem Lett. 2018. PMID: 29628327

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