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Quantitative analysis of orphan G protein-coupled receptor mRNAs by TaqMan Real-Time PCR: G2A and GPR4 lysophospholipid receptor expression in leukocytes and in a rat myocardial infarction-heart failure model.
Douglas SA, Ao Z, Johns DG, Maniscalco K, Willette RN, Sarov-Blat L, Cogswell JP, Seepersaud S, Murdock P, Steplewski KM, Patel L. Douglas SA, et al. Among authors: willette rn. Methods Mol Biol. 2005;306:27-49. doi: 10.1385/1-59259-927-3:027. Methods Mol Biol. 2005. PMID: 15867463 No abstract available.
PPARdelta activation normalizes cardiac substrate metabolism and reduces right ventricular hypertrophy in congestive heart failure.
Jucker BM, Doe CP, Schnackenberg CG, Olzinski AR, Maniscalco K, Williams C, Hu TC, Lenhard SC, Costell M, Bernard R, Sarov-Blat L, Steplewski K, Willette RN. Jucker BM, et al. Among authors: willette rn. J Cardiovasc Pharmacol. 2007 Jul;50(1):25-34. doi: 10.1097/FJC.0b013e31804b4163. J Cardiovasc Pharmacol. 2007. PMID: 17666912
Urotensin-II: a novel systemic hypertensive factor in the cat.
Behm DJ, Doe CP, Johns DG, Maniscalco K, Stankus GP, Wibberley A, Willette RN, Douglas SA. Behm DJ, et al. Among authors: willette rn. Naunyn Schmiedebergs Arch Pharmacol. 2004 Mar;369(3):274-80. doi: 10.1007/s00210-004-0873-1. Epub 2004 Feb 19. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 14985938
The peptidic urotensin-II receptor ligand GSK248451 possesses less intrinsic activity than the low-efficacy partial agonists SB-710411 and urantide in native mammalian tissues and recombinant cell systems.
Behm DJ, Stankus G, Doe CP, Willette RN, Sarau HM, Foley JJ, Schmidt DB, Nuthulaganti P, Fornwald JA, Ames RS, Lambert DG, Calo' G, Camarda V, Aiyar NV, Douglas SA. Behm DJ, et al. Among authors: willette rn. Br J Pharmacol. 2006 May;148(2):173-90. doi: 10.1038/sj.bjp.0706716. Br J Pharmacol. 2006. PMID: 16547525 Free PMC article.
Human urotensin-II is a potent vasoconstrictor and agonist for the orphan receptor GPR14.
Ames RS, Sarau HM, Chambers JK, Willette RN, Aiyar NV, Romanic AM, Louden CS, Foley JJ, Sauermelch CF, Coatney RW, Ao Z, Disa J, Holmes SD, Stadel JM, Martin JD, Liu WS, Glover GI, Wilson S, McNulty DE, Ellis CE, Elshourbagy NA, Shabon U, Trill JJ, Hay DW, Ohlstein EH, Bergsma DJ, Douglas SA. Ames RS, et al. Among authors: willette rn. Nature. 1999 Sep 16;401(6750):282-6. doi: 10.1038/45809. Nature. 1999. PMID: 10499587
148 results