Gómez-Lechón MJ - Search Results

1

Comparison of basal cytotoxicity data between mammalian and fish cell lines: a literature survey.

Castaño A, Gómez-Lechón MJ. Castaño A, et al. Toxicol In Vitro. 2005 Aug;19(5):695-705. doi: 10.1016/j.tiv.2005.04.002. Toxicol In Vitro. 2005. PMID: 15893445

2

Mechanism-based selection of compounds for the development of innovative in vitro approaches to hepatotoxicity studies in the LIINTOP project.

Gómez-Lechón MJ, Tolosa L, Castell JV, Donato MT. Gómez-Lechón MJ, et al. Toxicol In Vitro. 2010 Oct;24(7):1879-89. doi: 10.1016/j.tiv.2010.07.018. Epub 2010 Jul 23. Toxicol In Vitro. 2010. PMID: 20656008 Review.

3

Comparative analysis of eight cytotoxicity assays evaluated within the ACuteTox Project.

Clothier R, Gómez-Lechón MJ, Kinsner-Ovaskainen A, Kopp-Schneider A, O'Connor JE, Prieto P, Stanzel S. Clothier R, et al. Toxicol In Vitro. 2013 Jun;27(4):1347-56. doi: 10.1016/j.tiv.2012.08.015. Epub 2012 Aug 23. Toxicol In Vitro. 2013. PMID: 22951948

4

Diclofenac induces apoptosis in hepatocytes.

Gómez-Lechón MJ, Ponsoda X, O'Connor E, Donato T, Jover R, Castell JV. Gómez-Lechón MJ, et al. Toxicol In Vitro. 2003 Oct-Dec;17(5-6):675-80. doi: 10.1016/s0887-2333(03)00105-x. Toxicol In Vitro. 2003. PMID: 14599462

5

Semi-automatic quantitative RT-PCR to measure CYP induction by drugs in human hepatocytes.

Pérez G, Tabares B, Jover R, Gómez-Lechón MJ, Castell JV. Pérez G, et al. Toxicol In Vitro. 2003 Oct-Dec;17(5-6):643-9. doi: 10.1016/s0887-2333(03)00109-7. Toxicol In Vitro. 2003. PMID: 14599457

6

General Cytotoxicity Assessment by Means of the MTT Assay.

Tolosa L, Donato MT, Gómez-Lechón MJ. Tolosa L, et al. Methods Mol Biol. 2015;1250:333-48. doi: 10.1007/978-1-4939-2074-7_26. Methods Mol Biol. 2015. PMID: 26272156

7

Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development.

Donato MT, López-Riera M, Castell JV, Gómez-Lechón MJ, Jover R. Donato MT, et al. Toxicol Lett. 2016 Nov 30;263:58-67. doi: 10.1016/j.toxlet.2016.10.008. Epub 2016 Oct 17. Toxicol Lett. 2016. PMID: 27765674

8

Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies.

Castell JV, Jover R, Martínez-Jiménez CP, Gómez-Lechón MJ. Castell JV, et al. Expert Opin Drug Metab Toxicol. 2006 Apr;2(2):183-212. doi: 10.1517/17425255.2.2.183. Expert Opin Drug Metab Toxicol. 2006. PMID: 16866607 Review.

9

Identification of apoptotic drugs: multiparametric evaluation in cultured hepatocytes.

Gómez-Lechón MJ, O'Connor JE, Lahoz A, Castell JV, Donato MT. Gómez-Lechón MJ, et al. Curr Med Chem. 2008;15(20):2071-85. doi: 10.2174/092986708785132861. Curr Med Chem. 2008. PMID: 18691057 Review.

10

Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach.

Castell JV, Donato MT, Gómez-Lechón MJ. Castell JV, et al. Exp Toxicol Pathol. 2005 Jul;57 Suppl 1:189-204. doi: 10.1016/j.etp.2005.05.008. Exp Toxicol Pathol. 2005. PMID: 16092727 Review.

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