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Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement.
Okazawa A, Kanai T, Watanabe M, Yamazaki M, Inoue N, Ikeda M, Kurimoto M, Ishii H, Hibi T. Okazawa A, et al. Among authors: yamazaki m. Am J Gastroenterol. 2002 Dec;97(12):3108-17. doi: 10.1111/j.1572-0241.2002.07107.x. Am J Gastroenterol. 2002. PMID: 12492197
Role of the innate immune system in the development of chronic colitis.
Kanai T, Ilyama R, Ishikura T, Uraushihara K, Totsuka T, Yamazaki M, Nakamuma T, Watanabe M. Kanai T, et al. Among authors: yamazaki m. J Gastroenterol. 2002 Nov;37 Suppl 14:38-42. doi: 10.1007/BF03326411. J Gastroenterol. 2002. PMID: 12572864 Review.
Mucosal T cells as a target for treatment of IBD.
Watanabe M, Yamazaki M, Kanai T. Watanabe M, et al. Among authors: yamazaki m. J Gastroenterol. 2003 Mar;38 Suppl 15:48-50. J Gastroenterol. 2003. PMID: 12698871 Review.
Interleukin-18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin-18 transgenic mice.
Ishikura T, Kanai T, Uraushihara K, Iiyama R, Makita S, Totsuka T, Yamazaki M, Sawada T, Nakamura T, Miyata T, Kitahora T, Hibi T, Hoshino T, Watanabe M. Ishikura T, et al. Among authors: yamazaki m. J Gastroenterol Hepatol. 2003 Aug;18(8):960-9. doi: 10.1046/j.1440-1746.2003.03097.x. J Gastroenterol Hepatol. 2003. PMID: 12859727
3,810 results