Iwata N - Search Results

1

Oligomeric proteins ultrastructurally localize to cell processes, especially to axon terminals with higher density, but not to lipid rafts in Tg2576 mouse brain.

Kokubo H, Kayed R, Glabe CG, Saido TC, Iwata N, Helms JB, Yamaguchi H. Kokubo H, et al. Among authors: iwata n. Brain Res. 2005 May 31;1045(1-2):224-8. doi: 10.1016/j.brainres.2005.03.017. Epub 2005 Apr 25. Brain Res. 2005. PMID: 15910781

2

Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition.

Iwata N, Tsubuki S, Takaki Y, Watanabe K, Sekiguchi M, Hosoki E, Kawashima-Morishima M, Lee HJ, Hama E, Sekine-Aizawa Y, Saido TC. Iwata N, et al. Nat Med. 2000 Feb;6(2):143-50. doi: 10.1038/72237. Nat Med. 2000. PMID: 10655101

3

Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain.

Takaki Y, Iwata N, Tsubuki S, Taniguchi S, Toyoshima S, Lu B, Gerard NP, Gerard C, Lee HJ, Shirotani K, Saido TC. Takaki Y, et al. Among authors: iwata n. J Biochem. 2000 Dec;128(6):897-902. doi: 10.1093/oxfordjournals.jbchem.a022839. J Biochem. 2000. PMID: 11098130 Free article.

4

Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum.

Sekine-Aizawa Y, Hama E, Watanabe K, Tsubuki S, Kanai-Azuma M, Kanai Y, Arai H, Aizawa H, Iwata N, Saido TC. Sekine-Aizawa Y, et al. Among authors: iwata n. Eur J Neurosci. 2001 Mar;13(5):935-48. doi: 10.1046/j.0953-816x.2001.01462.x. Eur J Neurosci. 2001. PMID: 11264666

5

Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.

Shirotani K, Tsubuki S, Iwata N, Takaki Y, Harigaya W, Maruyama K, Kiryu-Seo S, Kiyama H, Iwata H, Tomita T, Iwatsubo T, Saido TC. Shirotani K, et al. Among authors: iwata n, iwata h. J Biol Chem. 2001 Jun 15;276(24):21895-901. doi: 10.1074/jbc.M008511200. Epub 2001 Mar 6. J Biol Chem. 2001. PMID: 11278416 Free article.

6

Metabolic regulation of brain Abeta by neprilysin.

Iwata N, Tsubuki S, Takaki Y, Shirotani K, Lu B, Gerard NP, Gerard C, Hama E, Lee HJ, Saido TC. Iwata N, et al. Science. 2001 May 25;292(5521):1550-2. doi: 10.1126/science.1059946. Science. 2001. PMID: 11375493

7

Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology.

Fukami S, Watanabe K, Iwata N, Haraoka J, Lu B, Gerard NP, Gerard C, Fraser P, Westaway D, St George-Hyslop P, Saido TC. Fukami S, et al. Among authors: iwata n. Neurosci Res. 2002 May;43(1):39-56. doi: 10.1016/s0168-0102(02)00015-9. Neurosci Res. 2002. PMID: 12074840

8

In vivo glioma growth requires host-derived matrix metalloproteinase 2 for maintenance of angioarchitecture.

Takahashi M, Fukami S, Iwata N, Inoue K, Itohara S, Itoh H, Haraoka J, Saido T. Takahashi M, et al. Among authors: iwata n. Pharmacol Res. 2002 Aug;46(2):155-63. doi: 10.1016/s1043-6618(02)00081-6. Pharmacol Res. 2002. PMID: 12220955

9

Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging.

Iwata N, Takaki Y, Fukami S, Tsubuki S, Saido TC. Iwata N, et al. J Neurosci Res. 2002 Nov 1;70(3):493-500. doi: 10.1002/jnr.10390. J Neurosci Res. 2002. PMID: 12391610

10

In vivo role of caspases in excitotoxic neuronal death: generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons.

Tomioka M, Shirotani K, Iwata N, Lee HJ, Yang F, Cole GM, Seyama Y, Saido TC. Tomioka M, et al. Among authors: iwata n. Brain Res Mol Brain Res. 2002 Dec;108(1-2):18-32. doi: 10.1016/s0169-328x(02)00486-2. Brain Res Mol Brain Res. 2002. PMID: 12480175

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