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CTLA-4 expressed by chemoresistant, as well as untreated, myeloid leukaemia cells can be targeted with ligands to induce apoptosis.
Laurent S, Palmisano GL, Martelli AM, Kato T, Tazzari PL, Pierri I, Clavio M, Dozin B, Balbi G, Megna M, Morabito A, Lamparelli T, Bacigalupo A, Gobbi M, Pistillo MP. Laurent S, et al. Among authors: palmisano gl. Br J Haematol. 2007 Feb;136(4):597-608. doi: 10.1111/j.1365-2141.2006.06472.x. Br J Haematol. 2007. PMID: 17367412 Free article.
Analysis of HLA-G expression in breast cancer tissues.
Palmisano GL, Pistillo MP, Fardin P, Capanni P, Nicolò G, Salvi S, Spina B, Pasciucco G, Ferrara GB. Palmisano GL, et al. Hum Immunol. 2002 Nov;63(11):969-76. doi: 10.1016/s0198-8859(02)00642-0. Hum Immunol. 2002. PMID: 12392849
CTLA-4 is not restricted to the lymphoid cell lineage and can function as a target molecule for apoptosis induction of leukemic cells.
Pistillo MP, Tazzari PL, Palmisano GL, Pierri I, Bolognesi A, Ferlito F, Capanni P, Polito L, Ratta M, Pileri S, Piccioli M, Basso G, Rissotto L, Conte R, Gobbi M, Stirpe F, Ferrara GB. Pistillo MP, et al. Among authors: palmisano gl. Blood. 2003 Jan 1;101(1):202-9. doi: 10.1182/blood-2002-06-1668. Epub 2002 Aug 15. Blood. 2003. PMID: 12393538 Free article.
Immunotoxins containing recombinant anti-CTLA-4 single-chain fragment variable antibodies and saporin: in vitro results and in vivo effects in an acute rejection model.
Tazzari PL, Polito L, Bolognesi A, Pistillo MP, Capanni P, Palmisano GL, Lemoli RM, Curti A, Biancone L, Camussi G, Conte R, Ferrara GB, Stirpe F. Tazzari PL, et al. Among authors: palmisano gl. J Immunol. 2001 Oct 15;167(8):4222-9. doi: 10.4049/jimmunol.167.8.4222. J Immunol. 2001. PMID: 11591743
Association of -318 C/T and +49 A/G cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms with a clinical subset of Italian patients with systemic sclerosis.
Balbi G, Ferrera F, Rizzi M, Piccioli P, Morabito A, Cardamone L, Ghio M, Palmisano GL, Carrara P, Pedemonte S, Sessarego M, De Angioletti M, Notaro R, Indiveri F, Pistillo MP. Balbi G, et al. Among authors: palmisano gl. Clin Exp Immunol. 2007 Jul;149(1):40-7. doi: 10.1111/j.1365-2249.2007.03394.x. Epub 2007 Apr 25. Clin Exp Immunol. 2007. PMID: 17459075 Free PMC article.
25 results