Sakane K - Search Results

1

Discovery of diphenylcarbamate derivatives as highly potent and selective IP receptor agonists: orally active prostacyclin mimetics. Part 3.

Hattori K, Tanaka A, Okitsu O, Tabuchi S, Taniguchi K, Nishio M, Koyama S, Higaki M, Seki J, Sakane K. Hattori K, et al. Among authors: sakane k. Bioorg Med Chem Lett. 2005 Jun 15;15(12):3091-5. doi: 10.1016/j.bmcl.2005.04.047. Bioorg Med Chem Lett. 2005. PMID: 15914004

2

Discovery of diphenyloxazole and Ndelta-Z-ornithine derivatives as highly potent and selective human prostaglandin EP(4) receptor antagonists.

Hattori K, Tanaka A, Fujii N, Takasugi H, Tenda Y, Tomita M, Nakazato S, Nakano K, Kato Y, Kono Y, Murai H, Sakane K. Hattori K, et al. Among authors: sakane k. J Med Chem. 2005 May 5;48(9):3103-6. doi: 10.1021/jm050085k. J Med Chem. 2005. PMID: 15857112

3

Metabolism investigation leading to novel drug design: orally active prostacyclin mimetics. Part 4.

Hattori K, Takamura F, Tanaka A, Takasugi H, Taniguchi K, Nishio M, Koyama S, Seki J, Sakane K. Hattori K, et al. Among authors: sakane k. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3284-7. doi: 10.1016/j.bmcl.2005.04.076. Bioorg Med Chem Lett. 2005. PMID: 15935659

4

Discovery of new diphenyloxazole derivatives containing a pyrrolidine ring: orally active prostacyclin mimetics. Part 2.

Hattori K, Okitsu O, Tabuchi S, Taniguchi K, Nishio M, Koyama S, Seki J, Sakane K. Hattori K, et al. Among authors: sakane k. Bioorg Med Chem Lett. 2005 Jul 1;15(13):3279-83. doi: 10.1016/j.bmcl.2005.04.042. Bioorg Med Chem Lett. 2005. PMID: 15935660

5

A novel pyridazinone derivative as a nonprostanoid PGI2 agonist.

Tsubaki K, Taniguchi K, Tabuchi S, Okitsu O, Hattori K, Seki J, Sakane K, Tanaka H. Tsubaki K, et al. Among authors: sakane k. Bioorg Med Chem Lett. 2000 Dec 18;10(24):2787-90. doi: 10.1016/s0960-894x(00)00571-0. Bioorg Med Chem Lett. 2000. PMID: 11133092

6

Synthesis and antibacterial evaluation of novel 2-[N-Imidoylpyrrolidinyl] carbapenems.

Hattori K, Yamada A, Kuroda S, Chiba T, Murata M, Sakane K. Hattori K, et al. Among authors: sakane k. Bioorg Med Chem Lett. 2002 Feb 11;12(3):383-6. doi: 10.1016/s0960-894x(01)00753-3. Bioorg Med Chem Lett. 2002. PMID: 11814802

7

Orally active cephalosporins. Part 2: synthesis, structure-activity relationships and oral absorption of cephalosporins having a C-3 pyridyl side chain.

Yamamoto H, Terasawa T, Nakamura A, Kawabata K, Sakane K, Matsumoto S, Matsumoto Y, Tawara S. Yamamoto H, et al. Among authors: sakane k. Bioorg Med Chem. 2000 May;8(5):1159-70. doi: 10.1016/s0968-0896(00)00021-3. Bioorg Med Chem. 2000. PMID: 10882026

8

Discovery of FR166124, a novel water-soluble pyrazolo-[1,5-a]pyridine adenosine A1 receptor antagonist.

Kuroda S, Akahane A, Itani H, Nishimura S, Durkin K, Kinoshita T, Tenda Y, Sakane K. Kuroda S, et al. Among authors: sakane k. Bioorg Med Chem Lett. 1999 Jul 19;9(14):1979-84. doi: 10.1016/s0960-894x(99)00304-2. Bioorg Med Chem Lett. 1999. PMID: 10450966

9

Orally active cephalosporins: synthesis, structure-activity relationships and oral absorption of 3-[(E) and (Z)-2-substituted vinyl]-cephalosporins.

Yamamoto H, Terasawa T, Ohki A, Shirai F, Kawabata K, Sakane K, Matsumoto S, Matsumoto Y, Tawara S. Yamamoto H, et al. Among authors: sakane k. Bioorg Med Chem. 2000 Jan;8(1):43-54. doi: 10.1016/s0968-0896(99)00257-6. Bioorg Med Chem. 2000. PMID: 10968263

10

Anti-Helicobacter pylori agents. 2. Structure activity relationships in a new series of 2-alkylguanidino-4-furylthiazoles.

Katsura Y, Nishino S, Tomishi T, Sakane K, Matsumoto Y, Ishikawa H, Takasugi H. Katsura Y, et al. Among authors: sakane k. Bioorg Med Chem Lett. 1998 Jun 2;8(11):1307-12. doi: 10.1016/s0960-894x(98)00206-6. Bioorg Med Chem Lett. 1998. PMID: 9871756

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