Nzila A - Search Results

1

Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy.

Nzila A, Ward SA, Marsh K, Sims PF, Hyde JE. Nzila A, et al. Trends Parasitol. 2005 Jun;21(6):292-8. doi: 10.1016/j.pt.2005.04.002. Trends Parasitol. 2005. PMID: 15922251 Free PMC article. Review.

2

Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites.

Nzila AM, Mberu EK, Sulo J, Dayo H, Winstanley PA, Sibley CH, Watkins WM. Nzila AM, et al. Antimicrob Agents Chemother. 2000 Apr;44(4):991-6. doi: 10.1128/AAC.44.4.991-996.2000. Antimicrob Agents Chemother. 2000. PMID: 10722502 Free PMC article.

3

Molecular evidence of greater selective pressure for drug resistance exerted by the long-acting antifolate Pyrimethamine/Sulfadoxine compared with the shorter-acting chlorproguanil/dapsone on Kenyan Plasmodium falciparum.

Nzila AM, Nduati E, Mberu EK, Hopkins Sibley C, Monks SA, Winstanley PA, Watkins WM. Nzila AM, et al. J Infect Dis. 2000 Jun;181(6):2023-8. doi: 10.1086/315520. Epub 2000 Jun 5. J Infect Dis. 2000. PMID: 10837185

4

Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?

Sibley CH, Hyde JE, Sims PF, Plowe CV, Kublin JG, Mberu EK, Cowman AF, Winstanley PA, Watkins WM, Nzila AM. Sibley CH, et al. Among authors: nzila am. Trends Parasitol. 2001 Dec;17(12):582-8. doi: 10.1016/s1471-4922(01)02085-2. Trends Parasitol. 2001. PMID: 11756042 Review.

5

Genetic diversity of Plasmodium falciparum parasites from Kenya is not affected by antifolate drug selection.

Nzila AM, Mberu EK, Nduati E, Ross A, Watkins WM, Sibley CH. Nzila AM, et al. Int J Parasitol. 2002 Nov;32(12):1469-76. doi: 10.1016/s0020-7519(02)00164-9. Int J Parasitol. 2002. PMID: 12392912 Clinical Trial.

6

Plasmodium falciparum: in vitro activity of sulfadoxine and dapsone in field isolates from Kenya: point mutations in dihydropteroate synthase may not be the only determinants in sulfa resistance.

Mberu EK, Nzila AM, Nduati E, Ross A, Monks SM, Kokwaro GO, Watkins WM, Hopkins Sibley C. Mberu EK, et al. Among authors: nzila am. Exp Parasitol. 2002 Jun-Jul;101(2-3):90-6. doi: 10.1016/s0014-4894(02)00108-x. Exp Parasitol. 2002. PMID: 12427462

7

Chemosensitization of Plasmodium falciparum by probenecid in vitro.

Nzila A, Mberu E, Bray P, Kokwaro G, Winstanley P, Marsh K, Ward S. Nzila A, et al. Antimicrob Agents Chemother. 2003 Jul;47(7):2108-12. doi: 10.1128/AAC.47.7.2108-2112.2003. Antimicrob Agents Chemother. 2003. PMID: 12821454 Free PMC article.

8

Antimalarial chemotherapy: young guns or back to the future?

Biagini GA, O'Neill PM, Nzila A, Ward SA, Bray PG. Biagini GA, et al. Among authors: nzila a. Trends Parasitol. 2003 Nov;19(11):479-87. doi: 10.1016/j.pt.2003.09.011. Trends Parasitol. 2003. PMID: 14580958 Review. No abstract available.

9

Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa.

Ochong E, Nzila A, Kimani S, Kokwaro G, Mutabingwa T, Watkins W, Marsh K. Ochong E, et al. Among authors: nzila a. Malar J. 2003 Dec 15;2(1):46. doi: 10.1186/1475-2875-2-46. Malar J. 2003. PMID: 14675491 Free PMC article.

10

In vitro activities of 2,4-diaminoquinazoline and 2,4-diaminopteridine derivatives against Plasmodium falciparum.

Ommeh S, Nduati E, Mberu E, Kokwaro G, Marsh K, Rosowsky A, Nzila A. Ommeh S, et al. Among authors: nzila a. Antimicrob Agents Chemother. 2004 Oct;48(10):3711-4. doi: 10.1128/AAC.48.10.3711-3714.2004. Antimicrob Agents Chemother. 2004. PMID: 15388424 Free PMC article.

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