Hartkoorn RC - Search Results

1

In vitro synergy and enhanced murine brain penetration of saquinavir coadministered with mefloquine.

Owen A, Janneh O, Hartkoorn RC, Chandler B, Bray PG, Martin P, Ward SA, Hart CA, Khoo SH, Back DJ. Owen A, et al. Among authors: hartkoorn rc. J Pharmacol Exp Ther. 2005 Sep;314(3):1202-9. doi: 10.1124/jpet.105.086272. Epub 2005 May 27. J Pharmacol Exp Ther. 2005. PMID: 15923343

2

Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir.

Janneh O, Hartkoorn RC, Jones E, Owen A, Ward SA, Davey R, Back DJ, Khoo SH. Janneh O, et al. Among authors: hartkoorn rc. Br J Pharmacol. 2008 Nov;155(6):875-83. doi: 10.1038/bjp.2008.320. Epub 2008 Aug 18. Br J Pharmacol. 2008. PMID: 19002102 Free PMC article.

3

Intracellular 'boosting' of darunavir using known transport inhibitors in primary PBMC.

Kwan WS, Janneh O, Hartkoorn R, Chandler B, Khoo S, Back D, Owen A. Kwan WS, et al. Br J Clin Pharmacol. 2009 Sep;68(3):375-80. doi: 10.1111/j.1365-2125.2009.03462.x. Br J Clin Pharmacol. 2009. PMID: 19740394 Free PMC article.

4

Modulation of the intracellular accumulation of saquinavir in peripheral blood mononuclear cells by inhibitors of MRP1, MRP2, P-gp and BCRP.

Janneh O, Owen A, Chandler B, Hartkoorn RC, Hart CA, Bray PG, Ward SA, Back DJ, Khoo SH. Janneh O, et al. Among authors: hartkoorn rc. AIDS. 2005 Dec 2;19(18):2097-102. doi: 10.1097/01.aids.0000194793.36175.40. AIDS. 2005. PMID: 16284458

5

Effect of transporter modulation on the emergence of nelfinavir resistance in vitro.

Chandler B, Detsika M, Owen A, Evans S, Hartkoorn RC, Cane PA, Back DJ, Khoo SH. Chandler B, et al. Among authors: hartkoorn rc. Antivir Ther. 2007;12(5):831-4. Antivir Ther. 2007. PMID: 17713167

6

Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes.

Janneh O, Chandler B, Hartkoorn R, Kwan WS, Jenkinson C, Evans S, Back DJ, Owen A, Khoo SH. Janneh O, et al. J Antimicrob Chemother. 2009 Nov;64(5):1002-7. doi: 10.1093/jac/dkp335. Epub 2009 Sep 11. J Antimicrob Chemother. 2009. PMID: 19748977

7

Differential drug susceptibility of intracellular and extracellular tuberculosis, and the impact of P-glycoprotein.

Hartkoorn RC, Chandler B, Owen A, Ward SA, Bertel Squire S, Back DJ, Khoo SH. Hartkoorn RC, et al. Tuberculosis (Edinb). 2007 May;87(3):248-55. doi: 10.1016/j.tube.2006.12.001. Epub 2007 Jan 26. Tuberculosis (Edinb). 2007. PMID: 17258938

8

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms.

Hartkoorn RC, Kwan WS, Shallcross V, Chaikan A, Liptrott N, Egan D, Sora ES, James CE, Gibbons S, Bray PG, Back DJ, Khoo SH, Owen A. Hartkoorn RC, et al. Pharmacogenet Genomics. 2010 Feb;20(2):112-20. doi: 10.1097/FPC.0b013e328335b02d. Pharmacogenet Genomics. 2010. PMID: 20051929 Free PMC article.

9

Down regulation of multidrug resistance protein-1 expression in patients with early rheumatoid arthritis exposed to methotrexate as a first disease-modifying antirheumatic drug.

Hider SL, Owen A, Hartkoorn R, Khoo S, Back D, Silman AJ, Bruce IN. Hider SL, et al. Ann Rheum Dis. 2006 Oct;65(10):1390-3. doi: 10.1136/ard.2005.049189. Epub 2006 Feb 27. Ann Rheum Dis. 2006. PMID: 16504991 Free PMC article.

10

Expression of P-glycoprotein, multidrug-resistance proteins 1 and 2 in CEM, CEM(VBL), CEM(E1000), MDCKII(MRP1) and MDCKII(MRP2) cell lines.

Owen A, Hartkoorn RC, Khoo S, Back D. Owen A, et al. Among authors: hartkoorn rc. AIDS. 2003 Oct 17;17(15):2276-8. doi: 10.1097/01.aids.0000088212.77946.65. AIDS. 2003. PMID: 14523293 No abstract available.

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