Chasteen ND - Search Results

1

Mutational analysis of C-lobe ligands of human serum transferrin: insights into the mechanism of iron release.

Mason AB, Halbrooks PJ, James NG, Connolly SA, Larouche JR, Smith VC, MacGillivray RT, Chasteen ND. Mason AB, et al. Among authors: chasteen nd. Biochemistry. 2005 Jun 7;44(22):8013-21. doi: 10.1021/bi050015f. Biochemistry. 2005. PMID: 15924420

2

Structural and functional consequences of the substitution of glycine 65 with arginine in the N-lobe of human transferrin.

Mason AB, Halbrooks PJ, James NG, Byrne SL, Grady JK, Chasteen ND, Bobst CE, Kaltashov IA, Smith VC, MacGillivray RT, Everse SJ. Mason AB, et al. Among authors: chasteen nd. Biochemistry. 2009 Mar 10;48(9):1945-53. doi: 10.1021/bi802254x. Biochemistry. 2009. PMID: 19219998 Free PMC article.

3

A loop in the N-lobe of human serum transferrin is critical for binding to the transferrin receptor as revealed by mutagenesis, isothermal titration calorimetry, and epitope mapping.

Mason AB, Byrne SL, Everse SJ, Roberts SE, Chasteen ND, Smith VC, MacGillivray RT, Kandemir B, Bou-Abdallah F. Mason AB, et al. Among authors: chasteen nd. J Mol Recognit. 2009 Nov-Dec;22(6):521-9. doi: 10.1002/jmr.979. J Mol Recognit. 2009. PMID: 19693784 Free PMC article.

4

The unique kinetics of iron release from transferrin: the role of receptor, lobe-lobe interactions, and salt at endosomal pH.

Byrne SL, Chasteen ND, Steere AN, Mason AB. Byrne SL, et al. Among authors: chasteen nd. J Mol Biol. 2010 Feb 12;396(1):130-40. doi: 10.1016/j.jmb.2009.11.023. Epub 2009 Nov 13. J Mol Biol. 2010. PMID: 19917294 Free PMC article.

5

Identification of a kinetically significant anion binding (KISAB) site in the N-lobe of human serum transferrin.

Byrne SL, Steere AN, Chasteen ND, Mason AB. Byrne SL, et al. Among authors: chasteen nd. Biochemistry. 2010 May 18;49(19):4200-7. doi: 10.1021/bi1003519. Biochemistry. 2010. PMID: 20397659 Free PMC article.

6

Evidence that His349 acts as a pH-inducible switch to accelerate receptor-mediated iron release from the C-lobe of human transferrin.

Steere AN, Byrne SL, Chasteen ND, Smith VC, MacGillivray RT, Mason AB. Steere AN, et al. Among authors: chasteen nd. J Biol Inorg Chem. 2010 Nov;15(8):1341-52. doi: 10.1007/s00775-010-0694-2. Epub 2010 Aug 14. J Biol Inorg Chem. 2010. PMID: 20711621 Free PMC article.

7

Kinetics of iron release from transferrin bound to the transferrin receptor at endosomal pH.

Steere AN, Byrne SL, Chasteen ND, Mason AB. Steere AN, et al. Among authors: chasteen nd. Biochim Biophys Acta. 2012 Mar;1820(3):326-33. doi: 10.1016/j.bbagen.2011.06.003. Epub 2011 Jun 15. Biochim Biophys Acta. 2012. PMID: 21699959 Free PMC article. Review.

8

How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.

Eckenroth BE, Steere AN, Chasteen ND, Everse SJ, Mason AB. Eckenroth BE, et al. Among authors: chasteen nd. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13089-94. doi: 10.1073/pnas.1105786108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788477 Free PMC article.

9

Ionic residues of human serum transferrin affect binding to the transferrin receptor and iron release.

Steere AN, Miller BF, Roberts SE, Byrne SL, Chasteen ND, Smith VC, MacGillivray RT, Mason AB. Steere AN, et al. Among authors: chasteen nd. Biochemistry. 2012 Jan 17;51(2):686-94. doi: 10.1021/bi201661g. Epub 2012 Jan 6. Biochemistry. 2012. PMID: 22191507 Free PMC article.

10

Structure-based mutagenesis reveals critical residues in the transferrin receptor participating in the mechanism of pH-induced release of iron from human serum transferrin.

Steere AN, Chasteen ND, Miller BF, Smith VC, MacGillivray RT, Mason AB. Steere AN, et al. Among authors: chasteen nd. Biochemistry. 2012 Mar 13;51(10):2113-21. doi: 10.1021/bi3001038. Epub 2012 Mar 1. Biochemistry. 2012. PMID: 22356162 Free PMC article.

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