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Human galanin (GAL) and galanin 1 receptor (GALR1) variations are not involved in fat intake and early onset obesity.
Schäuble N, Reichwald K, Grassl W, Bechstein H, Müller HC, Scherag A, Geller F, Utting M, Siegfried W, Goldschmidt H, Blundell J, Lawton C, Alam R, Whybrow S, Stubbs J, Platzer M, Hebebrand J, Hinney A. Schäuble N, et al. Among authors: scherag a. J Nutr. 2005 Jun;135(6):1387-92. doi: 10.1093/jn/135.6.1387. J Nutr. 2005. PMID: 15930442 Free article.
Lack of support for the association between GAD2 polymorphisms and severe human obesity.
Swarbrick MM, Waldenmaier B, Pennacchio LA, Lind DL, Cavazos MM, Geller F, Merriman R, Ustaszewska A, Malloy M, Scherag A, Hsueh WC, Rief W, Mauvais-Jarvis F, Pullinger CR, Kane JP, Dent R, McPherson R, Kwok PY, Hinney A, Hebebrand J, Vaisse C. Swarbrick MM, et al. Among authors: scherag a. PLoS Biol. 2005 Sep;3(9):e315. doi: 10.1371/journal.pbio.0030315. Epub 2005 Aug 30. PLoS Biol. 2005. PMID: 16122350 Free PMC article.
Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in children and adolescents with obsessive-compulsive disorder.
Mössner R, Walitza S, Geller F, Scherag A, Gutknecht L, Jacob C, Bogusch L, Remschmidt H, Simons M, Herpertz-Dahlmann B, Fleischhaker C, Schulz E, Warnke A, Hinney A, Wewetzer C, Lesch KP. Mössner R, et al. Among authors: scherag a. Int J Neuropsychopharmacol. 2006 Aug;9(4):437-42. doi: 10.1017/S1461145705005997. Epub 2005 Sep 7. Int J Neuropsychopharmacol. 2006. PMID: 16146581 Free article.
Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany.
Hinney A, Bettecken T, Tarnow P, Brumm H, Reichwald K, Lichtner P, Scherag A, Nguyen TT, Schlumberger P, Rief W, Vollmert C, Illig T, Wichmann HE, Schäfer H, Platzer M, Biebermann H, Meitinger T, Hebebrand J. Hinney A, et al. Among authors: scherag a. J Clin Endocrinol Metab. 2006 May;91(5):1761-9. doi: 10.1210/jc.2005-2056. Epub 2006 Feb 21. J Clin Endocrinol Metab. 2006. PMID: 16492696
Evidence for involvement of the vitamin D receptor gene in idiopathic short stature via a genome-wide linkage study and subsequent association studies.
Dempfle A, Wudy SA, Saar K, Hagemann S, Friedel S, Scherag A, Berthold LD, Alzen G, Gortner L, Blum WF, Hinney A, Nürnberg P, Schäfer H, Hebebrand J. Dempfle A, et al. Among authors: scherag a. Hum Mol Genet. 2006 Sep 15;15(18):2772-83. doi: 10.1093/hmg/ddl218. Epub 2006 Aug 11. Hum Mol Genet. 2006. PMID: 16905557
The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.
Lyon HN, Emilsson V, Hinney A, Heid IM, Lasky-Su J, Zhu X, Thorleifsson G, Gunnarsdottir S, Walters GB, Thorsteinsdottir U, Kong A, Gulcher J, Nguyen TT, Scherag A, Pfeufer A, Meitinger T, Brönner G, Rief W, Soto-Quiros ME, Avila L, Klanderman B, Raby BA, Silverman EK, Weiss ST, Laird N, Ding X, Groop L, Tuomi T, Isomaa B, Bengtsson K, Butler JL, Cooper RS, Fox CS, O'Donnell CJ, Vollmert C, Celedón JC, Wichmann HE, Hebebrand J, Stefansson K, Lange C, Hirschhorn JN. Lyon HN, et al. Among authors: scherag a. PLoS Genet. 2007 Apr 27;3(4):e61. doi: 10.1371/journal.pgen.0030061. Epub 2007 Mar 7. PLoS Genet. 2007. PMID: 17465681 Free PMC article.
Mutation screen and association studies in the diacylglycerol O-acyltransferase homolog 2 gene (DGAT2), a positional candidate gene for early onset obesity on chromosome 11q13.
Friedel S, Reichwald K, Scherag A, Brumm H, Wermter AK, Fries HR, Koberwitz K, Wabitsch M, Meitinger T, Platzer M, Biebermann H, Hinney A, Hebebrand J. Friedel S, et al. Among authors: scherag a. BMC Genet. 2007 May 3;8:17. doi: 10.1186/1471-2156-8-17. BMC Genet. 2007. PMID: 17477860 Free PMC article.
251 results