Zhang ZY - Search Results

1

Design, construction, and intracellular activation of an intramolecularly self-silenced signal transduction inhibitor.

Lee SY, Liang F, Guo XL, Xie L, Cahill SM, Blumenstein M, Yang H, Lawrence DS, Zhang ZY. Lee SY, et al. Among authors: zhang zy. Angew Chem Int Ed Engl. 2005 Jul 4;44(27):4242-4. doi: 10.1002/anie.200462004. Angew Chem Int Ed Engl. 2005. PMID: 15937885 No abstract available.

2

Design and characterization of an improved protein tyrosine phosphatase substrate-trapping mutant.

Xie L, Zhang YL, Zhang ZY. Xie L, et al. Among authors: zhang zy, zhang yl. Biochemistry. 2002 Mar 26;41(12):4032-9. doi: 10.1021/bi015904r. Biochemistry. 2002. PMID: 11900546

3

Modulation of protein kinase signaling by protein phosphatases and inhibitors.

Zhang ZY, Zhou B, Xie L. Zhang ZY, et al. Pharmacol Ther. 2002 Feb-Mar;93(2-3):307-17. doi: 10.1016/s0163-7258(02)00199-7. Pharmacol Ther. 2002. PMID: 12191622 Review.

4

Probing the molecular basis for potent and selective protein-tyrosine phosphatase 1B inhibition.

Guo XL, Shen K, Wang F, Lawrence DS, Zhang ZY. Guo XL, et al. Among authors: zhang zy. J Biol Chem. 2002 Oct 25;277(43):41014-22. doi: 10.1074/jbc.M207347200. Epub 2002 Aug 21. J Biol Chem. 2002. PMID: 12193602 Free article.

5

Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor.

Sun JP, Fedorov AA, Lee SY, Guo XL, Shen K, Lawrence DS, Almo SC, Zhang ZY. Sun JP, et al. Among authors: zhang zy. J Biol Chem. 2003 Apr 4;278(14):12406-14. doi: 10.1074/jbc.M212491200. Epub 2003 Jan 23. J Biol Chem. 2003. PMID: 12547827 Free article.

6

PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity.

Zhang ZY, Lee SY. Zhang ZY, et al. Expert Opin Investig Drugs. 2003 Feb;12(2):223-33. doi: 10.1517/13543784.12.2.223. Expert Opin Investig Drugs. 2003. PMID: 12556216 Review.

7

Aurintricarboxylic acid blocks in vitro and in vivo activity of YopH, an essential virulent factor of Yersinia pestis, the agent of plague.

Liang F, Huang Z, Lee SY, Liang J, Ivanov MI, Alonso A, Bliska JB, Lawrence DS, Mustelin T, Zhang ZY. Liang F, et al. Among authors: zhang zy. J Biol Chem. 2003 Oct 24;278(43):41734-41. doi: 10.1074/jbc.M307152200. Epub 2003 Jul 29. J Biol Chem. 2003. PMID: 12888560 Free article.

8

Residue 182 influences the second step of protein-tyrosine phosphatase-mediated catalysis.

Pedersen AK, Guo XL, Møller KB, Peters GH, Andersen HS, Kastrup JS, Mortensen SB, Iversen LF, Zhang ZY, Møller NP. Pedersen AK, et al. Among authors: zhang zy. Biochem J. 2004 Mar 1;378(Pt 2):421-33. doi: 10.1042/BJ20030565. Biochem J. 2004. PMID: 14572311 Free PMC article.

9

Cellular effects of small molecule PTP1B inhibitors on insulin signaling.

Xie L, Lee SY, Andersen JN, Waters S, Shen K, Guo XL, Moller NP, Olefsky JM, Lawrence DS, Zhang ZY. Xie L, et al. Among authors: zhang zy. Biochemistry. 2003 Nov 11;42(44):12792-804. doi: 10.1021/bi035238p. Biochemistry. 2003. PMID: 14596593

10

Structural and functional analysis of the costimulatory receptor programmed death-1.

Zhang X, Schwartz JC, Guo X, Bhatia S, Cao E, Lorenz M, Cammer M, Chen L, Zhang ZY, Edidin MA, Nathenson SG, Almo SC. Zhang X, et al. Among authors: zhang zy. Immunity. 2004 Mar;20(3):337-47. doi: 10.1016/s1074-7613(04)00051-2. Immunity. 2004. PMID: 15030777 Free article.

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