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Mutation analysis of the MCHR1 gene in human obesity.
Wermter AK, Reichwald K, Büch T, Geller F, Platzer C, Huse K, Hess C, Remschmidt H, Gudermann T, Preibisch G, Siegfried W, Goldschmidt HP, Li WD, Price RA, Biebermann H, Krude H, Vollmert C, Wichmann HE, Illig T, Sørensen TI, Astrup A, Larsen LH, Pedersen O, Eberlé D, Clément K, Blundell J, Wabitsch M, Schäfer H, Platzer M, Hinney A, Hebebrand J. Wermter AK, et al. Among authors: gudermann t. Eur J Endocrinol. 2005 Jun;152(6):851-62. doi: 10.1530/eje.1.01917. Eur J Endocrinol. 2005. PMID: 15941924
Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity.
Hinney A, Hohmann S, Geller F, Vogel C, Hess C, Wermter AK, Brokamp B, Goldschmidt H, Siegfried W, Remschmidt H, Schäfer H, Gudermann T, Hebebrand J. Hinney A, et al. Among authors: gudermann t. J Clin Endocrinol Metab. 2003 Sep;88(9):4258-67. doi: 10.1210/jc.2003-030233. J Clin Endocrinol Metab. 2003. PMID: 12970296 Free article. Clinical Trial.
Melanocortin-4 receptor gene variant I103 is negatively associated with obesity.
Geller F, Reichwald K, Dempfle A, Illig T, Vollmert C, Herpertz S, Siffert W, Platzer M, Hess C, Gudermann T, Biebermann H, Wichmann HE, Schäfer H, Hinney A, Hebebrand J. Geller F, et al. Among authors: gudermann t. Am J Hum Genet. 2004 Mar;74(3):572-81. doi: 10.1086/382490. Epub 2004 Feb 17. Am J Hum Genet. 2004. PMID: 14973783 Free PMC article.
Evolutionary aspects in evaluating mutations in the melanocortin 4 receptor.
Stäubert C, Tarnow P, Brumm H, Pitra C, Gudermann T, Grüters A, Schöneberg T, Biebermann H, Römpler H. Stäubert C, et al. Among authors: gudermann t. Endocrinology. 2007 Oct;148(10):4642-8. doi: 10.1210/en.2007-0138. Epub 2007 Jul 12. Endocrinology. 2007. PMID: 17628007
324 results