Cappai R - Search Results

1

Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway.

Cappai R, Leck SL, Tew DJ, Williamson NA, Smith DP, Galatis D, Sharples RA, Curtain CC, Ali FE, Cherny RA, Culvenor JG, Bottomley SP, Masters CL, Barnham KJ, Hill AF. Cappai R, et al. FASEB J. 2005 Aug;19(10):1377-9. doi: 10.1096/fj.04-3437fje. Epub 2005 Jun 9. FASEB J. 2005. PMID: 15946991

2

Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid.

Barnham KJ, Haeffner F, Ciccotosto GD, Curtain CC, Tew D, Mavros C, Beyreuther K, Carrington D, Masters CL, Cherny RA, Cappai R, Bush AI. Barnham KJ, et al. Among authors: cappai r. FASEB J. 2004 Sep;18(12):1427-9. doi: 10.1096/fj.04-1890fje. Epub 2004 Jul 1. FASEB J. 2004. PMID: 15231727

3

Plasma alpha-synuclein is decreased in subjects with Parkinson's disease.

Li QX, Mok SS, Laughton KM, McLean CA, Cappai R, Masters CL, Culvenor JG, Horne MK. Li QX, et al. Among authors: cappai r. Exp Neurol. 2007 Apr;204(2):583-8. doi: 10.1016/j.expneurol.2006.12.006. Epub 2006 Dec 19. Exp Neurol. 2007. PMID: 17258710

4

Formation of a high affinity lipid-binding intermediate during the early aggregation phase of alpha-synuclein.

Smith DP, Tew DJ, Hill AF, Bottomley SP, Masters CL, Barnham KJ, Cappai R. Smith DP, et al. Among authors: cappai r. Biochemistry. 2008 Feb 5;47(5):1425-34. doi: 10.1021/bi701522m. Epub 2008 Jan 8. Biochemistry. 2008. PMID: 18179253

5

Formation of dopamine-mediated alpha-synuclein-soluble oligomers requires methionine oxidation.

Leong SL, Pham CL, Galatis D, Fodero-Tavoletti MT, Perez K, Hill AF, Masters CL, Ali FE, Barnham KJ, Cappai R. Leong SL, et al. Among authors: cappai r. Free Radic Biol Med. 2009 May 15;46(10):1328-37. doi: 10.1016/j.freeradbiomed.2009.02.009. Epub 2009 Feb 25. Free Radic Biol Med. 2009. PMID: 19248830

6

Dopamine and the dopamine oxidation product 5,6-dihydroxylindole promote distinct on-pathway and off-pathway aggregation of alpha-synuclein in a pH-dependent manner.

Pham CL, Leong SL, Ali FE, Kenche VB, Hill AF, Gras SL, Barnham KJ, Cappai R. Pham CL, et al. Among authors: cappai r. J Mol Biol. 2009 Apr 3;387(3):771-85. doi: 10.1016/j.jmb.2009.02.007. Epub 2009 Feb 11. J Mol Biol. 2009. PMID: 19361420

7

Modulation of alpha-synuclein aggregation by dopamine: a review.

Leong SL, Cappai R, Barnham KJ, Pham CL. Leong SL, et al. Among authors: cappai r. Neurochem Res. 2009 Oct;34(10):1838-46. doi: 10.1007/s11064-009-9986-8. Epub 2009 May 15. Neurochem Res. 2009. PMID: 19444607 Review.

8

The structure of dopamine induced alpha-synuclein oligomers.

Rekas A, Knott RB, Sokolova A, Barnham KJ, Perez KA, Masters CL, Drew SC, Cappai R, Curtain CC, Pham CL. Rekas A, et al. Among authors: cappai r. Eur Biophys J. 2010 Sep;39(10):1407-19. doi: 10.1007/s00249-010-0595-x. Epub 2010 Mar 23. Eur Biophys J. 2010. PMID: 20309679

9

Guanidine hydrochloride denaturation of dopamine-induced α-synuclein oligomers: a small-angle X-ray scattering study.

Pham CL, Kirby N, Wood K, Ryan T, Roberts B, Sokolova A, Barnham KJ, Masters CL, Knott RB, Cappai R, Curtain CC, Rekas A. Pham CL, et al. Among authors: cappai r. Proteins. 2014 Jan;82(1):10-21. doi: 10.1002/prot.24332. Epub 2013 Aug 31. Proteins. 2014. PMID: 23733394

10

Alpha-synuclein oligomers and fibrils originate in two distinct conformer pools: a small angle X-ray scattering and ensemble optimisation modelling study.

Curtain CC, Kirby NM, Mertens HD, Barnham KJ, Knott RB, Masters CL, Cappai R, Rekas A, Kenche VB, Ryan T. Curtain CC, et al. Among authors: cappai r. Mol Biosyst. 2015 Jan;11(1):190-6. doi: 10.1039/c4mb00356j. Epub 2014 Oct 29. Mol Biosyst. 2015. PMID: 25352253

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