Leon C - Search Results

1

Effect of heat-treatment and the role of phospholipases on Fungizone-induced cytotoxicity within human kidney proximal tubular (HK-2) cells and Aspergillus fumigatus.

Leon C, Taylor R, Bartlett KH, Wasan KM. Leon C, et al. Int J Pharm. 2005 Jul 14;298(1):211-8. doi: 10.1016/j.ijpharm.2005.04.018. Int J Pharm. 2005. PMID: 15950412

2

Development and characterization of oral lipid-based amphotericin B formulations with enhanced drug solubility, stability and antifungal activity in rats infected with Aspergillus fumigatus or Candida albicans.

Wasan EK, Bartlett K, Gershkovich P, Sivak O, Banno B, Wong Z, Gagnon J, Gates B, Leon CG, Wasan KM. Wasan EK, et al. Int J Pharm. 2009 May 8;372(1-2):76-84. doi: 10.1016/j.ijpharm.2009.01.003. Epub 2009 Jan 17. Int J Pharm. 2009. PMID: 19236839

3

Differences in human phospholipid transfer protein activity following incubation of Fungizone compared to lipid-based Amphotericin-B formulations in normolipidemic and hyperlipidemic plasma.

Henderson RJ, Leon CG, Wasan KM. Henderson RJ, et al. Drug Dev Ind Pharm. 2009 Sep;35(9):1139-46. doi: 10.1080/03639040902824852. Drug Dev Ind Pharm. 2009. PMID: 19381990

4

In vitro cytotoxicity of two novel oral formulations of Amphotericin B (iCo-009 and iCo-010) against Candida albicans, human monocytic and kidney cell lines.

Leon CG, Lee J, Bartlett K, Gershkovich P, Wasan EK, Zhao J, Clement JG, Wasan KM. Leon CG, et al. Lipids Health Dis. 2011 Aug 20;10:144. doi: 10.1186/1476-511X-10-144. Lipids Health Dis. 2011. PMID: 21854638 Free PMC article.

5

Pharmacokinetics and biodistribution of amphotericin B in rats following oral administration in a novel lipid-based formulation.

Gershkovich P, Wasan EK, Lin M, Sivak O, Leon CG, Clement JG, Wasan KM. Gershkovich P, et al. J Antimicrob Chemother. 2009 Jul;64(1):101-8. doi: 10.1093/jac/dkp140. Epub 2009 Apr 27. J Antimicrob Chemother. 2009. PMID: 19398459

6

Modifications in low-density lipoprotein receptor expression affects Cyclosporin A cellular uptake and cytotoxicity.

Leon C, Jia J, Qiu G, Hill JS, Wasan KM. Leon C, et al. J Pharm Sci. 2008 Jun;97(6):2350-61. doi: 10.1002/jps.21141. J Pharm Sci. 2008. PMID: 17823952

7

Potential role of acyl-coenzyme A:cholesterol transferase (ACAT) Inhibitors as hypolipidemic and antiatherosclerosis drugs.

Leon C, Hill JS, Wasan KM. Leon C, et al. Pharm Res. 2005 Oct;22(10):1578-88. doi: 10.1007/s11095-005-6306-0. Epub 2005 Sep 22. Pharm Res. 2005. PMID: 16180116 Review.

8

Androgen-mediated cholesterol metabolism in LNCaP and PC-3 cell lines is regulated through two different isoforms of acyl-coenzyme A:Cholesterol Acyltransferase (ACAT).

Locke JA, Wasan KM, Nelson CC, Guns ES, Leon CG. Locke JA, et al. Among authors: leon cg. Prostate. 2008 Jan 1;68(1):20-33. doi: 10.1002/pros.20674. Prostate. 2008. PMID: 18000807

9

Discovery and development of toll-like receptor 4 (TLR4) antagonists: a new paradigm for treating sepsis and other diseases.

Leon CG, Tory R, Jia J, Sivak O, Wasan KM. Leon CG, et al. Pharm Res. 2008 Aug;25(8):1751-61. doi: 10.1007/s11095-008-9571-x. Epub 2008 May 21. Pharm Res. 2008. PMID: 18493843 Free PMC article. Review.

10

Haptoglobin inhibits phospholipid transfer protein activity in hyperlipidemic human plasma.

Henderson RJ, Wasan KM, Leon CG. Henderson RJ, et al. Lipids Health Dis. 2009 Jul 23;8:27. doi: 10.1186/1476-511X-8-27. Lipids Health Dis. 2009. PMID: 19627602 Free PMC article.

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