Zanger UM - Search Results

1

Contribution of CYP3A5 to the in vitro hepatic clearance of tacrolimus.

Kamdem LK, Streit F, Zanger UM, Brockmöller J, Oellerich M, Armstrong VW, Wojnowski L. Kamdem LK, et al. Among authors: zanger um. Clin Chem. 2005 Aug;51(8):1374-81. doi: 10.1373/clinchem.2005.050047. Epub 2005 Jun 10. Clin Chem. 2005. PMID: 15951320

2

Limited contribution of CYP3A5 to the hepatic 6beta-hydroxylation of testosterone.

Kamdem LK, Meineke I, Koch I, Zanger UM, Brockmöller J, Wojnowski L. Kamdem LK, et al. Among authors: zanger um. Naunyn Schmiedebergs Arch Pharmacol. 2004 Jul;370(1):71-7. doi: 10.1007/s00210-004-0944-3. Epub 2004 Jul 1. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 15232676

3

The induction of cytochrome P450 3A5 (CYP3A5) in the human liver and intestine is mediated by the xenobiotic sensors pregnane X receptor (PXR) and constitutively activated receptor (CAR).

Burk O, Koch I, Raucy J, Hustert E, Eichelbaum M, Brockmöller J, Zanger UM, Wojnowski L. Burk O, et al. Among authors: zanger um. J Biol Chem. 2004 Sep 10;279(37):38379-85. doi: 10.1074/jbc.M404949200. Epub 2004 Jul 12. J Biol Chem. 2004. PMID: 15252010 Free article.

4

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.

Burk O, Tegude H, Koch I, Hustert E, Wolbold R, Glaeser H, Klein K, Fromm MF, Nuessler AK, Neuhaus P, Zanger UM, Eichelbaum M, Wojnowski L. Burk O, et al. Among authors: zanger um. J Biol Chem. 2002 Jul 5;277(27):24280-8. doi: 10.1074/jbc.M202345200. Epub 2002 Apr 8. J Biol Chem. 2002. PMID: 11940601 Free article.

5

Genetic signature consistent with selection against the CYP3A4*1B allele in non-African populations.

Schirmer M, Toliat MR, Haberl M, Suk A, Kamdem LK, Klein K, Brockmöller J, Nürnberg P, Zanger UM, Wojnowski L. Schirmer M, et al. Among authors: zanger um. Pharmacogenet Genomics. 2006 Jan;16(1):59-71. doi: 10.1097/01.fpc.0000182779.03180.ba. Pharmacogenet Genomics. 2006. PMID: 16344723

6

Sex-dependent genetic markers of CYP3A4 expression and activity in human liver microsomes.

Schirmer M, Rosenberger A, Klein K, Kulle B, Toliat MR, Nürnberg P, Zanger UM, Wojnowski L. Schirmer M, et al. Among authors: zanger um. Pharmacogenomics. 2007 May;8(5):443-53. doi: 10.2217/14622416.8.5.443. Pharmacogenomics. 2007. PMID: 17465708

7

The genetic determinants of the CYP3A5 polymorphism.

Hustert E, Haberl M, Burk O, Wolbold R, He YQ, Klein K, Nuessler AC, Neuhaus P, Klattig J, Eiselt R, Koch I, Zibat A, Brockmöller J, Halpert JR, Zanger UM, Wojnowski L. Hustert E, et al. Among authors: zanger um. Pharmacogenetics. 2001 Dec;11(9):773-9. doi: 10.1097/00008571-200112000-00005. Pharmacogenetics. 2001. PMID: 11740341

8

Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA.

Koch I, Weil R, Wolbold R, Brockmöller J, Hustert E, Burk O, Nuessler A, Neuhaus P, Eichelbaum M, Zanger U, Wojnowski L. Koch I, et al. Drug Metab Dispos. 2002 Oct;30(10):1108-14. doi: 10.1124/dmd.30.10.1108. Drug Metab Dispos. 2002. PMID: 12228187

9

Carbonyl reductase 1 is a predominant doxorubicin reductase in the human liver.

Kassner N, Huse K, Martin HJ, Gödtel-Armbrust U, Metzger A, Meineke I, Brockmöller J, Klein K, Zanger UM, Maser E, Wojnowski L. Kassner N, et al. Among authors: zanger um. Drug Metab Dispos. 2008 Oct;36(10):2113-20. doi: 10.1124/dmd.108.022251. Epub 2008 Jul 17. Drug Metab Dispos. 2008. PMID: 18635746

10

Bupropion and 4-OH-bupropion pharmacokinetics in relation to genetic polymorphisms in CYP2B6.

Kirchheiner J, Klein C, Meineke I, Sasse J, Zanger UM, Mürdter TE, Roots I, Brockmöller J. Kirchheiner J, et al. Among authors: zanger um. Pharmacogenetics. 2003 Oct;13(10):619-26. doi: 10.1097/00008571-200310000-00005. Pharmacogenetics. 2003. PMID: 14515060

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