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The peptide Trp-Lys-Tyr-Met-Val-D-Met activates neutrophils through the formyl peptide receptor only when signaling through the formylpeptide receptor like 1 is blocked. A receptor switch with implications for signal transduction studies with inhibitors and receptor antagonists.
Karlsson J, Fu H, Boulay F, Bylund J, Dahlgren C. Karlsson J, et al. Biochem Pharmacol. 2006 May 14;71(10):1488-96. doi: 10.1016/j.bcp.2006.02.010. Epub 2006 Mar 6. Biochem Pharmacol. 2006. PMID: 16549058
A monocyte-specific peptide from herpes simplex virus type 2 glycoprotein G activates the NADPH-oxidase but not chemotaxis through a G-protein-coupled receptor distinct from the members of the formyl peptide receptor family.
Bellner L, Karlsson J, Fu H, Boulay F, Dahlgren C, Eriksson K, Karlsson A. Bellner L, et al. Among authors: karlsson j, karlsson a. J Immunol. 2007 Nov 1;179(9):6080-7. doi: 10.4049/jimmunol.179.9.6080. J Immunol. 2007. PMID: 17947682
1,867 results