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β2-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression.
Hofbauer D, Mougiakakos D, Broggini L, Zaiss M, Büttner-Herold M, Bach C, Spriewald B, Neumann F, Bisht S, Nolting J, Zeiser R, Hamarsheh S, Eberhardt M, Vera J, Visentin C, De Luca CMG, Moda F, Haskamp S, Flamann C, Böttcher M, Bitterer K, Völkl S, Mackensen A, Ricagno S, Bruns H. Hofbauer D, et al. Among authors: bottcher m. Immunity. 2021 Aug 10;54(8):1772-1787.e9. doi: 10.1016/j.immuni.2021.07.002. Epub 2021 Jul 20. Immunity. 2021. PMID: 34289378 Free article.
Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids.
Auger JP, Zimmermann M, Faas M, Stifel U, Chambers D, Krishnacoumar B, Taudte RV, Grund C, Erdmann G, Scholtysek C, Uderhardt S, Ben Brahim O, Pascual Maté M, Stoll C, Böttcher M, Palumbo-Zerr K, Mangan MSJ, Dzamukova M, Kieler M, Hofmann M, Blüml S, Schabbauer G, Mougiakakos D, Sonnewald U, Hartmann F, Simon D, Kleyer A, Grüneboom A, Finotto S, Latz E, Hofmann J, Schett G, Tuckermann J, Krönke G. Auger JP, et al. Among authors: bottcher m. Nature. 2024 May;629(8010):184-192. doi: 10.1038/s41586-024-07282-7. Epub 2024 Apr 10. Nature. 2024. PMID: 38600378
PD-L1/PD-1: new kid on the "immune metabolic" block.
Qorraj M, Böttcher M, Mougiakakos D. Qorraj M, et al. Among authors: bottcher m. Oncotarget. 2017 Sep 5;8(43):73364-73365. doi: 10.18632/oncotarget.20639. eCollection 2017 Sep 26. Oncotarget. 2017. PMID: 29088710 Free PMC article. No abstract available.
482 results