Kuil AJ - Search Results

1

In vivo RNA interference-mediated ablation of MDR1 P-glycoprotein.

Pichler A, Zelcer N, Prior JL, Kuil AJ, Piwnica-Worms D. Pichler A, et al. Among authors: kuil aj. Clin Cancer Res. 2005 Jun 15;11(12):4487-94. doi: 10.1158/1078-0432.CCR-05-0038. Clin Cancer Res. 2005. PMID: 15958634 Free article.

2

Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter.

Zelcer N, Saeki T, Bot I, Kuil A, Borst P. Zelcer N, et al. Biochem J. 2003 Jan 1;369(Pt 1):23-30. doi: 10.1042/BJ20021081. Biochem J. 2003. PMID: 12220224 Free PMC article.

3

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.

Zelcer N, van de Wetering K, Hillebrand M, Sarton E, Kuil A, Wielinga PR, Tephly T, Dahan A, Beijnen JH, Borst P. Zelcer N, et al. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7274-9. doi: 10.1073/pnas.0502530102. Epub 2005 May 10. Proc Natl Acad Sci U S A. 2005. PMID: 15886284 Free PMC article.

4

Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).

Zelcer N, Huisman MT, Reid G, Wielinga P, Breedveld P, Kuil A, Knipscheer P, Schellens JH, Schinkel AH, Borst P. Zelcer N, et al. J Biol Chem. 2003 Jun 27;278(26):23538-44. doi: 10.1074/jbc.M303504200. Epub 2003 Apr 17. J Biol Chem. 2003. PMID: 12702717 Free article.

5

The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.

Reid G, Wielinga P, Zelcer N, van der Heijden I, Kuil A, de Haas M, Wijnholds J, Borst P. Reid G, et al. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9244-9. doi: 10.1073/pnas.1033060100. Epub 2003 Jun 30. Proc Natl Acad Sci U S A. 2003. PMID: 12835412 Free PMC article.

6

Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

Zelcer N, Reid G, Wielinga P, Kuil A, van der Heijden I, Schuetz JD, Borst P. Zelcer N, et al. Biochem J. 2003 Apr 15;371(Pt 2):361-7. doi: 10.1042/BJ20021886. Biochem J. 2003. PMID: 12523936 Free PMC article.

7

Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides.

van de Wetering K, Zelcer N, Kuil A, Feddema W, Hillebrand M, Vlaming ML, Schinkel AH, Beijnen JH, Borst P. van de Wetering K, et al. Mol Pharmacol. 2007 Aug;72(2):387-94. doi: 10.1124/mol.107.035592. Epub 2007 May 7. Mol Pharmacol. 2007. PMID: 17485564

8

Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

Zelcer N, van de Wetering K, de Waart R, Scheffer GL, Marschall HU, Wielinga PR, Kuil A, Kunne C, Smith A, van der Valk M, Wijnholds J, Elferink RO, Borst P. Zelcer N, et al. J Hepatol. 2006 Apr;44(4):768-75. doi: 10.1016/j.jhep.2005.07.022. Epub 2005 Aug 9. J Hepatol. 2006. PMID: 16225954

9

The effect of low pH on breast cancer resistance protein (ABCG2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mitoxantrone, topotecan, and resveratrol in in vitro drug transport models.

Breedveld P, Pluim D, Cipriani G, Dahlhaus F, van Eijndhoven MA, de Wolf CJ, Kuil A, Beijnen JH, Scheffer GL, Jansen G, Borst P, Schellens JH. Breedveld P, et al. Mol Pharmacol. 2007 Jan;71(1):240-9. doi: 10.1124/mol.106.028167. Epub 2006 Oct 10. Mol Pharmacol. 2007. PMID: 17032904

10

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

Wielinga PR, Reid G, Challa EE, van der Heijden I, van Deemter L, de Haas M, Mol C, Kuil AJ, Groeneveld E, Schuetz JD, Brouwer C, De Abreu RA, Wijnholds J, Beijnen JH, Borst P. Wielinga PR, et al. Among authors: kuil aj. Mol Pharmacol. 2002 Dec;62(6):1321-31. doi: 10.1124/mol.62.6.1321. Mol Pharmacol. 2002. PMID: 12435799

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