Lu P - Search Results

1

Bioactivation of 2,3-diaminopyridine-containing bradykinin B1 receptor antagonists: irreversible binding to liver microsomal proteins and formation of glutathione conjugates.

Tang C, Subramanian R, Kuo Y, Krymgold S, Lu P, Kuduk SD, Ng C, Feng DM, Elmore C, Soli E, Ho J, Bock MG, Baillie TA, Prueksaritanont T. Tang C, et al. Among authors: lu p. Chem Res Toxicol. 2005 Jun;18(6):934-45. doi: 10.1021/tx0500427. Chem Res Toxicol. 2005. PMID: 15962928

2

Metabolic interactions between mibefradil and HMG-CoA reductase inhibitors: an in vitro investigation with human liver preparations.

Prueksaritanont T, Ma B, Tang C, Meng Y, Assang C, Lu P, Reider PJ, Lin JH, Baillie TA. Prueksaritanont T, et al. Among authors: lu p. Br J Clin Pharmacol. 1999 Mar;47(3):291-8. doi: 10.1046/j.1365-2125.1999.00903.x. Br J Clin Pharmacol. 1999. PMID: 10215754 Free PMC article.

3

Interspecies comparison and role of human cytochrome P450 and flavin-containing monooxygenase in hepatic metabolism of L-775,606, a potent 5-HT(1D) receptor agonist.

Prueksaritanont T, Lu P, Gorham L, Sternfeld F, Vyas KP. Prueksaritanont T, et al. Among authors: lu p. Xenobiotica. 2000 Jan;30(1):47-59. doi: 10.1080/004982500237811. Xenobiotica. 2000. PMID: 10659950

4

Metabolism of rofecoxib in vitro using human liver subcellular fractions.

Slaughter D, Takenaga N, Lu P, Assang C, Walsh DJ, Arison BH, Cui D, Halpin RA, Geer LA, Vyas KP, Baillie TA. Slaughter D, et al. Among authors: lu p. Drug Metab Dispos. 2003 Nov;31(11):1398-408. doi: 10.1124/dmd.31.11.1398. Drug Metab Dispos. 2003. PMID: 14570773

5

Testosterone, 7-benzyloxyquinoline, and 7-benzyloxy-4-trifluoromethyl-coumarin bind to different domains within the active site of cytochrome P450 3A4.

Lu P, Lin Y, Rodrigues AD, Rushmore TH, Baillie TA, Shou M. Lu P, et al. Drug Metab Dispos. 2001 Nov;29(11):1473-9. Drug Metab Dispos. 2001. PMID: 11602524

6

Enzyme kinetics of cytochrome P450-mediated reactions.

Shou M, Lin Y, Lu P, Tang C, Mei Q, Cui D, Tang W, Ngui JS, Lin CC, Singh R, Wong BK, Yergey JA, Lin JH, Pearson PG, Baillie TA, Rodrigues AD, Rushmore TH. Shou M, et al. Among authors: lu p. Curr Drug Metab. 2001 Mar;2(1):17-36. doi: 10.2174/1389200013338784. Curr Drug Metab. 2001. PMID: 11465149 Review.

7

Monoclonal antibodies with identical Fc sequences can bind to FcRn differentially with pharmacokinetic consequences.

Wang W, Lu P, Fang Y, Hamuro L, Pittman T, Carr B, Hochman J, Prueksaritanont T. Wang W, et al. Among authors: lu p. Drug Metab Dispos. 2011 Sep;39(9):1469-77. doi: 10.1124/dmd.111.039453. Epub 2011 May 24. Drug Metab Dispos. 2011. PMID: 21610128

8

Substrate inhibition kinetics for cytochrome P450-catalyzed reactions.

Lin Y, Lu P, Tang C, Mei Q, Sandig G, Rodrigues AD, Rushmore TH, Shou M. Lin Y, et al. Among authors: lu p. Drug Metab Dispos. 2001 Apr;29(4 Pt 1):368-74. Drug Metab Dispos. 2001. PMID: 11259318

9

Cytochrome P450 3A4 is the major enzyme involved in the metabolism of the substance P receptor antagonist aprepitant.

Sanchez RI, Wang RW, Newton DJ, Bakhtiar R, Lu P, Chiu SH, Evans DC, Huskey SE. Sanchez RI, et al. Among authors: lu p. Drug Metab Dispos. 2004 Nov;32(11):1287-92. doi: 10.1124/dmd.104.000216. Epub 2004 Aug 10. Drug Metab Dispos. 2004. PMID: 15304427

10

Selective inhibition of dog hepatic CYP2B11 and CYP3A12.

Lu P, Singh SB, Carr BA, Fang Y, Xiang CD, Rushmore TH, Rodrigues AD, Shou M. Lu P, et al. J Pharmacol Exp Ther. 2005 May;313(2):518-28. doi: 10.1124/jpet.104.077651. Epub 2005 Jan 26. J Pharmacol Exp Ther. 2005. PMID: 15677349

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