Zimmermann J - Search Results

1

Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2.

Tirat A, Schilb A, Riou V, Leder L, Gerhartz B, Zimmermann J, Worpenberg S, Eidhoff U, Freuler F, Stettler T, Mayr L, Ottl J, Leuenberger B, Filipuzzi I. Tirat A, et al. Among authors: zimmermann j. Anal Biochem. 2005 Aug 15;343(2):244-55. doi: 10.1016/j.ab.2005.04.023. Anal Biochem. 2005. PMID: 15963938

2

High-content assay to study protein prenylation.

Simonen M, Ibig-Rehm Y, Hofmann G, Zimmermann J, Albrecht G, Magnier M, Heidinger V, Gabriel D. Simonen M, et al. Among authors: zimmermann j. J Biomol Screen. 2008 Jul;13(6):456-67. doi: 10.1177/1087057108318757. Epub 2008 May 28. J Biomol Screen. 2008. PMID: 18509097

3

Structure-based optimisation of 2-aminobenzylstatine derivatives: potent and selective inhibitors of the chymotrypsin-like activity of the human 20S proteasome.

Furet P, Imbach P, Fuerst P, Lang M, Noorani M, Zimmermann J, García-Echeverría C. Furet P, et al. Among authors: zimmermann j. Bioorg Med Chem Lett. 2002 May 20;12(10):1331-4. doi: 10.1016/s0960-894x(02)00178-6. Bioorg Med Chem Lett. 2002. PMID: 11992770

4

Entry into a new class of potent proteasome inhibitors having high antiproliferative activity by structure-based design.

Furet P, Imbach P, Noorani M, Koeppler J, Laumen K, Lang M, Guagnano V, Fuerst P, Roesel J, Zimmermann J, García-Echeverría C. Furet P, et al. Among authors: zimmermann j. J Med Chem. 2004 Sep 23;47(20):4810-3. doi: 10.1021/jm049660v. J Med Chem. 2004. PMID: 15369383 Free article.

5

In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase.

García-Echeverría C, Pearson MA, Marti A, Meyer T, Mestan J, Zimmermann J, Gao J, Brueggen J, Capraro HG, Cozens R, Evans DB, Fabbro D, Furet P, Porta DG, Liebetanz J, Martiny-Baron G, Ruetz S, Hofmann F. García-Echeverría C, et al. Among authors: zimmermann j. Cancer Cell. 2004 Mar;5(3):231-9. doi: 10.1016/s1535-6108(04)00051-0. Cancer Cell. 2004. PMID: 15050915 Free article.

6

The insulin-like growth factor-I receptor inhibitor NVP-AEW541 provokes cell cycle arrest and apoptosis in multiple myeloma cells.

Maiso P, Ocio EM, Garayoa M, Montero JC, Hofmann F, García-Echeverría C, Zimmermann J, Pandiella A, San Miguel JF. Maiso P, et al. Among authors: zimmermann j. Br J Haematol. 2008 May;141(4):470-82. doi: 10.1111/j.1365-2141.2008.07049.x. Epub 2008 Mar 12. Br J Haematol. 2008. PMID: 18341634 Free article.

7

Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.

Marzinzik AL, Amstutz R, Bold G, Bourgier E, Cotesta S, Glickman JF, Götte M, Henry C, Lehmann S, Hartwieg JC, Ofner S, Pellé X, Roddy TP, Rondeau JM, Stauffer F, Stout SJ, Widmer A, Zimmermann J, Zoller T, Jahnke W. Marzinzik AL, et al. Among authors: zimmermann j. ChemMedChem. 2015 Nov;10(11):1884-91. doi: 10.1002/cmdc.201500338. Epub 2015 Sep 18. ChemMedChem. 2015. PMID: 26381451

8

Inhibition of insulin-like growth factor-I receptor (IGF-IR) using NVP-AEW541, a small molecule kinase inhibitor, reduces orthotopic pancreatic cancer growth and angiogenesis.

Moser C, Schachtschneider P, Lang SA, Gaumann A, Mori A, Zimmermann J, Schlitt HJ, Geissler EK, Stoeltzing O. Moser C, et al. Among authors: zimmermann j. Eur J Cancer. 2008 Jul;44(11):1577-86. doi: 10.1016/j.ejca.2008.04.003. Epub 2008 Apr 27. Eur J Cancer. 2008. PMID: 18445520

9

Targeting cathepsin K diminishes prostate cancer establishment and growth in murine bone.

Liang W, Wang F, Chen Q, Dai J, Escara-Wilke J, Keller ET, Zimmermann J, Hong N, Lu Y, Zhang J. Liang W, et al. Among authors: zimmermann j. J Cancer Res Clin Oncol. 2019 Aug;145(8):1999-2012. doi: 10.1007/s00432-019-02950-y. Epub 2019 Jun 6. J Cancer Res Clin Oncol. 2019. PMID: 31172267 Free PMC article.

10

CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer.

Xiang J, Hurchla MA, Fontana F, Su X, Amend SR, Esser AK, Douglas GJ, Mudalagiriyappa C, Luker KE, Pluard T, Ademuyiwa FO, Romagnoli B, Tuffin G, Chevalier E, Luker GD, Bauer M, Zimmermann J, Aft RL, Dembowsky K, Weilbaecher KN. Xiang J, et al. Among authors: zimmermann j. Mol Cancer Ther. 2015 Nov;14(11):2473-85. doi: 10.1158/1535-7163.MCT-15-0252. Epub 2015 Aug 12. Mol Cancer Ther. 2015. PMID: 26269605 Free PMC article.

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