Groffen J - Search Results

1

Generation of rac3 null mutant mice: role of Rac3 in Bcr/Abl-caused lymphoblastic leukemia.

Cho YJ, Zhang B, Kaartinen V, Haataja L, de Curtis I, Groffen J, Heisterkamp N. Cho YJ, et al. Among authors: groffen j. Mol Cell Biol. 2005 Jul;25(13):5777-85. doi: 10.1128/MCB.25.13.5777-5785.2005. Mol Cell Biol. 2005. PMID: 15964830 Free PMC article.

2

The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading.

Haataja L, Kaartinen V, Groffen J, Heisterkamp N. Haataja L, et al. Among authors: groffen j. J Biol Chem. 2002 Mar 8;277(10):8321-8. doi: 10.1074/jbc.M105363200. Epub 2001 Dec 27. J Biol Chem. 2002. PMID: 11756406 Free article.

3

Interaction of the small GTPase Rac3 with NRBP, a protein with a kinase-homology domain.

De Langhe S, Haataja L, Senadheera D, Groffen J, Heisterkamp N. De Langhe S, et al. Among authors: groffen j. Int J Mol Med. 2002 May;9(5):451-9. Int J Mol Med. 2002. PMID: 11956649

4

BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl.

Hemmeryckx B, Reichert A, Watanabe M, Kaartinen V, de Jong R, Pattengale PK, Groffen J, Heisterkamp N. Hemmeryckx B, et al. Among authors: groffen j. Oncogene. 2002 May 9;21(20):3225-31. doi: 10.1038/sj.onc.1205452. Oncogene. 2002. PMID: 12082638

5

Targeted expression of activated Rac3 in mammary epithelium leads to defective postlactational involution and benign mammary gland lesions.

Leung K, Nagy A, Gonzalez-Gomez I, Groffen J, Heisterkamp N, Kaartinen V. Leung K, et al. Among authors: groffen j. Cells Tissues Organs. 2003;175(2):72-83. doi: 10.1159/000073751. Cells Tissues Organs. 2003. PMID: 14605486

6

Scambio, a novel guanine nucleotide exchange factor for Rho.

Curtis C, Hemmeryckx B, Haataja L, Senadheera D, Groffen J, Heisterkamp N. Curtis C, et al. Among authors: groffen j. Mol Cancer. 2004 Apr 23;3:10. doi: 10.1186/1476-4598-3-10. Mol Cancer. 2004. PMID: 15107133 Free PMC article.

7

Resistance to farnesyltransferase inhibitors in Bcr/Abl-positive lymphoblastic leukemia by increased expression of a novel ABC transporter homolog ATP11a.

Zhang B, Groffen J, Heisterkamp N. Zhang B, et al. Among authors: groffen j. Blood. 2005 Aug 15;106(4):1355-61. doi: 10.1182/blood-2004-09-3655. Epub 2005 Apr 28. Blood. 2005. PMID: 15860663 Free PMC article.

8

Interaction of Bcr/Abl with C3G, an exchange factor for the small GTPase Rap1, through the adapter protein Crkl.

Cho YJ, Hemmeryckx B, Groffen J, Heisterkamp N. Cho YJ, et al. Among authors: groffen j. Biochem Biophys Res Commun. 2005 Aug 12;333(4):1276-83. doi: 10.1016/j.bbrc.2005.06.030. Biochem Biophys Res Commun. 2005. PMID: 15982636

9

Resistance to imatinib of bcr/abl p190 lymphoblastic leukemia cells.

Mishra S, Zhang B, Cunnick JM, Heisterkamp N, Groffen J. Mishra S, et al. Among authors: groffen j. Cancer Res. 2006 May 15;66(10):5387-93. doi: 10.1158/0008-5472.CAN-05-3058. Cancer Res. 2006. PMID: 16707466

10

Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.

Cho YJ, Cunnick JM, Yi SJ, Kaartinen V, Groffen J, Heisterkamp N. Cho YJ, et al. Among authors: groffen j. Mol Cell Biol. 2007 Feb;27(3):899-911. doi: 10.1128/MCB.00756-06. Epub 2006 Nov 20. Mol Cell Biol. 2007. PMID: 17116687 Free PMC article.

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