Johansson PO - Search Results

1

Design and synthesis of potent inhibitors of plasmepsin I and II: X-ray crystal structure of inhibitor in complex with plasmepsin II.

Johansson PO, Lindberg J, Blackman MJ, Kvarnström I, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Johansson PO, et al. J Med Chem. 2005 Jun 30;48(13):4400-9. doi: 10.1021/jm040884n. J Med Chem. 2005. PMID: 15974592

2

Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifs.

Johansson PO, Chen Y, Belfrage AK, Blackman MJ, Kvarnström I, Jansson K, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Johansson PO, et al. J Med Chem. 2004 Jun 17;47(13):3353-66. doi: 10.1021/jm031106i. J Med Chem. 2004. PMID: 15189032

3

Potent inhibitors of the hepatitis C virus NS3 protease: use of a novel P2 cyclopentane-derived template.

Johansson PO, Bäck M, Kvarnström I, Jansson K, Vrang L, Hamelink E, Hallberg A, Rosenquist A, Samuelsson B. Johansson PO, et al. Bioorg Med Chem. 2006 Aug 1;14(15):5136-51. doi: 10.1016/j.bmc.2006.04.008. Epub 2006 May 3. Bioorg Med Chem. 2006. PMID: 16675222

4

Novel potent macrocyclic inhibitors of the hepatitis C virus NS3 protease: use of cyclopentane and cyclopentene P2-motifs.

Bäck M, Johansson PO, Wångsell F, Thorstensson F, Kvarnström I, Ayesa S, Wähling H, Pelcman M, Jansson K, Lindström S, Wallberg H, Classon B, Rydergård C, Vrang L, Hamelink E, Hallberg A, Rosenquist S, Samuelsson B. Bäck M, et al. Among authors: johansson po. Bioorg Med Chem. 2007 Nov 15;15(22):7184-202. doi: 10.1016/j.bmc.2007.07.027. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17845856

5

Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: design, synthesis and X-ray crystal structures of enzyme inhibitor complexes.

Sandgren V, Agback T, Johansson PO, Lindberg J, Kvarnström I, Samuelsson B, Belda O, Dahlgren A. Sandgren V, et al. Among authors: johansson po. Bioorg Med Chem. 2012 Jul 15;20(14):4377-89. doi: 10.1016/j.bmc.2012.05.039. Epub 2012 May 24. Bioorg Med Chem. 2012. PMID: 22698785 Free article.

6

Novel morpholinone-based D-Phe-Pro-Arg mimics as potential thrombin inhibitors: design, synthesis, and X-ray crystal structure of an enzyme inhibitor complex.

Dahlgren A, Johansson PO, Kvarnström I, Musil D, Nilsson I, Samuelsson B. Dahlgren A, et al. Among authors: johansson po. Bioorg Med Chem. 2002 Jun;10(6):1829-39. doi: 10.1016/s0968-0896(02)00023-8. Bioorg Med Chem. 2002. PMID: 11937341

7

Discovery of novel, potent and bioavailable proline-urea based macrocyclic HCV NS3/4A protease inhibitors.

Vendeville S, Nilsson M, de Kock H, Lin TI, Antonov D, Classon B, Ayesa S, Ivanov V, Johansson PO, Kahnberg P, Eneroth A, Wikstrom K, Vrang L, Edlund M, Lindström S, Van de Vreken W, McGowan D, Tahri A, Hu L, Lenz O, Delouvroy F, Van Dooren M, Kindermans N, Surleraux D, Wigerinck P, Rosenquist A, Samuelsson B, Simmen K, Raboisson P. Vendeville S, et al. Among authors: johansson po. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6189-93. doi: 10.1016/j.bmcl.2008.10.004. Epub 2008 Oct 5. Bioorg Med Chem Lett. 2008. PMID: 18954982

8

Discovery and development of simeprevir (TMC435), a HCV NS3/4A protease inhibitor.

Rosenquist Å, Samuelsson B, Johansson PO, Cummings MD, Lenz O, Raboisson P, Simmen K, Vendeville S, de Kock H, Nilsson M, Horvath A, Kalmeijer R, de la Rosa G, Beumont-Mauviel M. Rosenquist Å, et al. Among authors: johansson po. J Med Chem. 2014 Mar 13;57(5):1673-93. doi: 10.1021/jm401507s. Epub 2014 Feb 14. J Med Chem. 2014. PMID: 24446688

9

Microeconomic surplus in health care: applied economic theory in health care in four European countries.

Walzer S, Nuijten M, Wiesner C, Kaier K, Johansson PO, Oertel S. Walzer S, et al. Among authors: johansson po. Front Pharmacol. 2013 Feb 18;4:17. doi: 10.3389/fphar.2013.00017. eCollection 2013. Front Pharmacol. 2013. PMID: 23423475 Free PMC article.

10

The value of a statistical life: theoretical and empirical evidence.

Johansson PO. Johansson PO. Appl Health Econ Health Policy. 2002;1(1):33-41. Appl Health Econ Health Policy. 2002. PMID: 14618746 Review.

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