Ahn SK - Search Results

1

Asymmetric synthesis of 1,3-dioxolane-pyrimidine nucleosides and their anti-HIV activity.

Kim HO, Ahn SK, Alves AJ, Beach JW, Jeong LS, Choi BG, Van Roey P, Schinazi RF, Chu CK. Kim HO, et al. Among authors: ahn sk. J Med Chem. 1992 May 29;35(11):1987-95. doi: 10.1021/jm00089a007. J Med Chem. 1992. PMID: 1597854

2

Synthesis and structure-activity relationships of 6-substituted 2',3'-dideoxypurine nucleosides as potential anti-human immunodeficiency virus agents.

Chu CK, Ullas GV, Jeong LS, Ahn SK, Doboszewski B, Lin ZX, Beach JW, Schinazi RF. Chu CK, et al. Among authors: ahn sk. J Med Chem. 1990 Jun;33(6):1553-61. doi: 10.1021/jm00168a006. J Med Chem. 1990. PMID: 2342052

3

Polypharmacology of N⁶-(3-Iodobenzyl)adenosine-5'-N-methyluronamide (IB-MECA) and Related A₃ Adenosine Receptor Ligands: Peroxisome Proliferator Activated Receptor (PPAR) γ Partial Agonist and PPARδ Antagonist Activity Suggests Their Antidiabetic Potential.

Yu J, Ahn S, Kim HJ, Lee M, Ahn S, Kim J, Jin SH, Lee E, Kim G, Cheong JH, Jacobson KA, Jeong LS, Noh M. Yu J, et al. J Med Chem. 2017 Sep 14;60(17):7459-7475. doi: 10.1021/acs.jmedchem.7b00805. Epub 2017 Aug 28. J Med Chem. 2017. PMID: 28799755 Free PMC article.

4

2-Phenyl-8-(1-phenylallyl)-chromenone compounds have a pan-PPAR modulator pharmacophore.

Ahn S, Kim J, An S, Pyo JJ, Jung D, Lee J, Hwang SY, Gong J, Shin I, Kim HP, Kim H, Noh M. Ahn S, et al. Bioorg Med Chem. 2019 Jul 1;27(13):2948-2958. doi: 10.1016/j.bmc.2019.05.028. Epub 2019 May 17. Bioorg Med Chem. 2019. PMID: 31128991

5

Selenium bioisosteric replacement of adenosine derivatives promoting adiponectin secretion increases the binding affinity to peroxisome proliferator-activated receptor δ.

An S, Yu J, Choi H, Ko H, Ahn S, Shin JC, Pyo JJ, Jeong LS, Noh M. An S, et al. Bioorg Med Chem. 2020 Jan 1;28(1):115226. doi: 10.1016/j.bmc.2019.115226. Epub 2019 Nov 28. Bioorg Med Chem. 2020. PMID: 31806266

6

Discovery and Structure-Activity Relationships of Novel Template, Truncated 1'-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators.

An S, Kim G, Kim HJ, Ahn S, Kim HY, Ko H, Hyun YE, Nguyen M, Jeong J, Liu Z, Han J, Choi H, Yu J, Kim JW, Lee HW, Jacobson KA, Cho WJ, Kim YM, Kang KW, Noh M, Jeong LS. An S, et al. J Med Chem. 2020 Dec 24;63(24):16012-16027. doi: 10.1021/acs.jmedchem.0c01874. Epub 2020 Dec 16. J Med Chem. 2020. PMID: 33325691 Free PMC article.

7

Galangin 3-benzyl-5-methylether derivatives function as an adiponectin synthesis-promoting peroxisome proliferator-activated receptor γ partial agonist.

Ko H, Jang H, An S, Park IG, Ahn S, Gong J, Hwang SY, Oh S, Kwak SY, Choi WJ, Kim H, Noh M. Ko H, et al. Bioorg Med Chem. 2022 Jan 15;54:116564. doi: 10.1016/j.bmc.2021.116564. Epub 2021 Dec 15. Bioorg Med Chem. 2022. PMID: 34922307

8

Novel linked butanolide dimer compounds increase adiponectin production during adipogenesis in human mesenchymal stem cells through peroxisome proliferator-activated receptor γ modulation.

Ahn S, Basavana Gowda MK, Lee M, Masagalli JN, Mailar K, Choi WJ, Noh M. Ahn S, et al. Eur J Med Chem. 2020 Feb 1;187:111969. doi: 10.1016/j.ejmech.2019.111969. Epub 2019 Dec 14. Eur J Med Chem. 2020. PMID: 31865018

9

Prenylated Chrysin Derivatives as Partial PPARγ Agonists with Adiponectin Secretion-Inducing Activity.

An S, Ko H, Jang H, Park IG, Ahn S, Hwang SY, Gong J, Oh S, Kwak SY, Lee Y, Kim H, Noh M. An S, et al. ACS Med Chem Lett. 2023 Mar 6;14(4):425-431. doi: 10.1021/acsmedchemlett.2c00511. eCollection 2023 Apr 13. ACS Med Chem Lett. 2023. PMID: 37077388 Free PMC article.

10

Kojyl cinnamate esters are peroxisome proliferator-activated receptor α/γ dual agonists.

Kim SO, Han Y, Ahn S, An S, Shin JC, Choi H, Kim HJ, Park NH, Kim YJ, Jin SH, Rho HS, Noh M. Kim SO, et al. Bioorg Med Chem. 2018 Nov 15;26(21):5654-5663. doi: 10.1016/j.bmc.2018.10.010. Epub 2018 Oct 17. Bioorg Med Chem. 2018. PMID: 30352713

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