Torrens A - Search Results

1

A preliminary study of the metabolic stability of a series of benzoxazinone derivatives as potent neuropeptide Y5 antagonists.

Dordal A, Lipkin M, Macritchie J, Mas J, Port A, Rose S, Salgado L, Savic V, Schmidt W, Serafini MT, Spearing W, Torrens A, Yeste S. Dordal A, et al. Among authors: torrens a. Bioorg Med Chem Lett. 2005 Aug 15;15(16):3679-84. doi: 10.1016/j.bmcl.2005.05.103. Bioorg Med Chem Lett. 2005. PMID: 15982873

2

7-Azetidinylquinolones as antibacterial agents. 3. Synthesis, properties and structure-activity relationships of the stereoisomers containing a 7-(3-amino-2-methyl-1-azetidinyl) moiety.

Frigola J, Vañó D, Torrens A, Gómez-Gomar A, Ortega E, García-Granda S. Frigola J, et al. Among authors: torrens a. J Med Chem. 1995 Mar 31;38(7):1203-15. doi: 10.1021/jm00007a017. J Med Chem. 1995. PMID: 7707323

3

7-azetidinylquinolones as antibacterial agents. 2. Synthesis and biological activity of 7-(2,3-disubstituted-1-azetidinyl)-4-oxoquinoline- and -1,8-naphthyridine-3-carboxylic acids. Properties and structure-activity relationships of quinolones with an azetidine moiety.

Frigola J, Torrens A, Castrillo JA, Mas J, Vañó D, Berrocal JM, Calvet C, Salgado L, Redondo J, García-Granda S, et al. Frigola J, et al. Among authors: torrens a. J Med Chem. 1994 Nov 25;37(24):4195-210. doi: 10.1021/jm00050a016. J Med Chem. 1994. PMID: 7990118

4

7-Azetidinylquinolones as antibacterial agents. Synthesis and structure-activity relationships.

Frigola J, Parés J, Corbera J, Vañó D, Mercè R, Torrens A, Más J, Valentí E. Frigola J, et al. Among authors: torrens a. J Med Chem. 1993 Apr 2;36(7):801-10. doi: 10.1021/jm00059a002. J Med Chem. 1993. PMID: 8464033

5

Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands.

Holenz J, Mercè R, Díaz JL, Guitart X, Codony X, Dordal A, Romero G, Torrens A, Mas J, Andaluz B, Hernández S, Monroy X, Sánchez E, Hernández E, Pérez R, Cubí R, Sanfeliu O, Buschmann H. Holenz J, et al. Among authors: torrens a. J Med Chem. 2005 Mar 24;48(6):1781-95. doi: 10.1021/jm049615n. J Med Chem. 2005. PMID: 15771424

6

Synthesis of new benzoxazinone derivatives as neuropeptide Y5 antagonists for the treatment of obesity.

Torrens A, Mas J, Port A, Castrillo JA, Sanfeliu O, Guitart X, Dordal A, Romero G, Fisas MA, Sánchez E, Hernández E, Pérez P, Pérez R, Buschmann H. Torrens A, et al. J Med Chem. 2005 Mar 24;48(6):2080-92. doi: 10.1021/jm049599u. J Med Chem. 2005. PMID: 15771450

7

Selective sigma-1 (sigma1) receptor antagonists: emerging target for the treatment of neuropathic pain.

Díaz JL, Zamanillo D, Corbera J, Baeyens JM, Maldonado R, Pericàs MA, Vela JM, Torrens A. Díaz JL, et al. Among authors: torrens a. Cent Nerv Syst Agents Med Chem. 2009 Sep;9(3):172-83. doi: 10.2174/1871524910909030172. Cent Nerv Syst Agents Med Chem. 2009. PMID: 20021351 Review.

8

Synthesis and structure-activity relationship study of a new series of selective σ(1) receptor ligands for the treatment of pain: 4-aminotriazoles.

Díaz JL, Christmann U, Fernández A, Torrens A, Port A, Pascual R, Álvarez I, Burgueño J, Monroy X, Montero A, Balada A, Vela JM, Almansa C. Díaz JL, et al. Among authors: torrens a. J Med Chem. 2015 Mar 12;58(5):2441-51. doi: 10.1021/jm501920g. Epub 2015 Feb 19. J Med Chem. 2015. PMID: 25658964

9

EST64454: a Highly Soluble σ₁ Receptor Antagonist Clinical Candidate for Pain Management.

Díaz JL, García M, Torrens A, Caamaño AM, Enjo J, Sicre C, Lorente A, Port A, Montero A, Yeste S, Álvarez I, Martín M, Maldonado R, de la Puente B, Vidal-Torres A, Cendán CM, Vela JM, Almansa C. Díaz JL, et al. Among authors: torrens a. J Med Chem. 2020 Dec 10;63(23):14979-14988. doi: 10.1021/acs.jmedchem.0c01575. Epub 2020 Nov 25. J Med Chem. 2020. PMID: 33237785

10

Towards Multitargeted Ligands as Pain Therapeutics: Dual Ligands of the Ca_vα2δ-1 Subunit of Voltage-Gated Calcium Channel and the μ-Opioid Receptor.

Wegert A, Monnee M, de Graaf W, van Holst F, Bolcato G, Díaz JL, Dordal A, Portillo-Salido E, Reinoso RF, Yeste S, Torrens A, Almansa C. Wegert A, et al. Among authors: torrens a. ChemMedChem. 2024 May 17;19(10):e202300473. doi: 10.1002/cmdc.202300473. Epub 2024 Jan 17. ChemMedChem. 2024. PMID: 38230842

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