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Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus.
Behrens TW, Graham RR, Kyogoku C, Baechler EC, Ramos PS, Gillett C, Bauer J, Ortmann WA, Hippen KL, Peterson E, Langefeld CD, Moser KL, Gaffney PM, Gregersen PK. Behrens TW, et al. Among authors: kyogoku c. Novartis Found Symp. 2005;267:145-60; discussion 160-4. doi: 10.1002/047002139x.ch10. Novartis Found Symp. 2005. PMID: 15999805
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.
Kyogoku C, Langefeld CD, Ortmann WA, Lee A, Selby S, Carlton VE, Chang M, Ramos P, Baechler EC, Batliwalla FM, Novitzke J, Williams AH, Gillett C, Rodine P, Graham RR, Ardlie KG, Gaffney PM, Moser KL, Petri M, Begovich AB, Gregersen PK, Behrens TW. Kyogoku C, et al. Am J Hum Genet. 2004 Sep;75(3):504-7. doi: 10.1086/423790. Epub 2004 Jul 23. Am J Hum Genet. 2004. PMID: 15273934 Free PMC article.
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.
Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, Baechler EC, Plenge RM, Koeuth T, Ortmann WA, Hom G, Bauer JW, Gillett C, Burtt N, Cunninghame Graham DS, Onofrio R, Petri M, Gunnarsson I, Svenungsson E, Rönnblom L, Nordmark G, Gregersen PK, Moser K, Gaffney PM, Criswell LA, Vyse TJ, Syvänen AC, Bohjanen PR, Daly MJ, Behrens TW, Altshuler D. Graham RR, et al. Among authors: kyogoku c. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6758-63. doi: 10.1073/pnas.0701266104. Epub 2007 Apr 5. Proc Natl Acad Sci U S A. 2007. PMID: 17412832 Free PMC article.
Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE.
Graham RR, Ortmann W, Rodine P, Espe K, Langefeld C, Lange E, Williams A, Beck S, Kyogoku C, Moser K, Gaffney P, Gregersen PK, Criswell LA, Harley JB, Behrens TW. Graham RR, et al. Among authors: kyogoku c. Eur J Hum Genet. 2007 Aug;15(8):823-30. doi: 10.1038/sj.ejhg.5201827. Epub 2007 Apr 4. Eur J Hum Genet. 2007. PMID: 17406641
26 results