Aldrich JV - Search Results

1

[Nalpha-benzylTyr1,cyclo(D-Asp5,Dap8)]- dynorphin A-(1-11)NH2 cyclized in the "address" domain is a novel kappa-opioid receptor antagonist.

Patkar KA, Yan X, Murray TF, Aldrich JV. Patkar KA, et al. Among authors: aldrich jv. J Med Chem. 2005 Jul 14;48(14):4500-3. doi: 10.1021/jm050105i. J Med Chem. 2005. PMID: 15999987

2

Synthesis and opioid activity of 2-substituted dynorphin A-(1-13) amide analogues.

Story SC, Murray TF, Delander GE, Aldrich JV. Story SC, et al. Among authors: aldrich jv. Int J Pept Protein Res. 1992 Aug;40(2):89-96. doi: 10.1111/j.1399-3011.1992.tb01454.x. Int J Pept Protein Res. 1992. PMID: 1359999

3

Effect of modification of the basic residues of dynorphin A-(1-13) amide on kappa opioid receptor selectivity and opioid activity.

Snyder KR, Story SC, Heidt ME, Murray TF, DeLander GE, Aldrich JV. Snyder KR, et al. Among authors: aldrich jv. J Med Chem. 1992 Nov 13;35(23):4330-3. doi: 10.1021/jm00101a010. J Med Chem. 1992. PMID: 1360025

4

N-terminal alkylated derivatives of [D-Pro10]dynorphin A-(1-11) are highly selective for kappa-opioid receptors.

Choi H, Murray TF, DeLander GE, Caldwell V, Aldrich JV. Choi H, et al. Among authors: aldrich jv. J Med Chem. 1992 Nov 27;35(24):4638-9. doi: 10.1021/jm00102a019. J Med Chem. 1992. PMID: 1361580 No abstract available.

5

Synthesis and opioid activity of conformationally constrained dynorphin A analogues. 1. Conformational constraint in the "message" sequence.

Arttamangkul S, Murray TF, DeLander GE, Aldrich JV. Arttamangkul S, et al. Among authors: aldrich jv. J Med Chem. 1995 Jun 23;38(13):2410-7. doi: 10.1021/jm00013a016. J Med Chem. 1995. PMID: 7608905

6

Synthesis and opioid activity of dynorphin A-(1-13)NH2 analogues containing cis- and trans-4-aminocyclohexanecarboxylic acid.

Snyder KR, Murray TF, DeLander GE, Aldrich JV. Snyder KR, et al. Among authors: aldrich jv. J Med Chem. 1993 Apr 16;36(8):1100-3. doi: 10.1021/jm00060a018. J Med Chem. 1993. PMID: 8097539

7

Synthesis and opioid activity of dynorphin A-(1-13)NH2 analogues containing cis- and trans-4-aminocyclohexanecarboxylic acid.

Snyder KR, Murray TF, DeLander GE, Aldrich JV. Snyder KR, et al. Among authors: aldrich jv. J Med Chem. 1993 Jun 25;36(13):1921-2. doi: 10.1021/jm00065a602. J Med Chem. 1993. PMID: 8099977 No abstract available.

8

Synthesis and opioid activity of conformationally constrained dynorphin A analogues. 2. Conformational constraint in the "address" sequence.

Arttamangkul S, Ishmael JE, Murray TF, Grandy DK, DeLander GE, Kieffer BL, Aldrich JV. Arttamangkul S, et al. Among authors: aldrich jv. J Med Chem. 1997 Apr 11;40(8):1211-8. doi: 10.1021/jm960753p. J Med Chem. 1997. PMID: 9111295

9

Synthesis and opioid activity of [D-Pro10]dynorphin A-(1-11) analogues with N-terminal alkyl substitution.

Choi H, Murray TF, DeLander GE, Schmidt WK, Aldrich JV. Choi H, et al. Among authors: aldrich jv. J Med Chem. 1997 Aug 15;40(17):2733-9. doi: 10.1021/jm960747t. J Med Chem. 1997. PMID: 9276018

10

N-alkylated derivatives of [D-Pro10]dynorphin A-(1-11) are high affinity partial agonists at the cloned rat kappa-opioid receptor.

Soderstrom K, Choi H, Berman FW, Aldrich JV, Murray TF. Soderstrom K, et al. Among authors: aldrich jv. Eur J Pharmacol. 1997 Nov 5;338(2):191-7. doi: 10.1016/s0014-2999(97)81948-6. Eur J Pharmacol. 1997. PMID: 9456002

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