Umezawa K - Search Results

1

Dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, induces apoptosis in multiple myeloma cells in an IkappaBalpha-independent manner.

Tatetsu H, Okuno Y, Nakamura M, Matsuno F, Sonoki T, Taniguchi I, Uneda S, Umezawa K, Mitsuya H, Hata H. Tatetsu H, et al. Among authors: umezawa k. Mol Cancer Ther. 2005 Jul;4(7):1114-20. doi: 10.1158/1535-7163.MCT-04-0198. Mol Cancer Ther. 2005. PMID: 16020669

2

A novel NF-kappaB inhibitor DHMEQ selectively targets constitutive NF-kappaB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo.

Watanabe M, Dewan MZ, Okamura T, Sasaki M, Itoh K, Higashihara M, Mizoguchi H, Honda M, Sata T, Watanabe T, Yamamoto N, Umezawa K, Horie R. Watanabe M, et al. Among authors: umezawa k. Int J Cancer. 2005 Mar 10;114(1):32-8. doi: 10.1002/ijc.20688. Int J Cancer. 2005. PMID: 15523684

3

Biscoclaurine alkaloid cepharanthine inhibits the growth of primary effusion lymphoma in vitro and in vivo and induces apoptosis via suppression of the NF-kappaB pathway.

Takahashi-Makise N, Suzu S, Hiyoshi M, Ohsugi T, Katano H, Umezawa K, Okada S. Takahashi-Makise N, et al. Among authors: umezawa k. Int J Cancer. 2009 Sep 15;125(6):1464-72. doi: 10.1002/ijc.24521. Int J Cancer. 2009. PMID: 19521981

4

DHMEQ, a new NF-kappaB inhibitor, induces apoptosis and enhances fludarabine effects on chronic lymphocytic leukemia cells.

Horie R, Watanabe M, Okamura T, Taira M, Shoda M, Motoji T, Utsunomiya A, Watanabe T, Higashihara M, Umezawa K. Horie R, et al. Among authors: umezawa k. Leukemia. 2006 May;20(5):800-6. doi: 10.1038/sj.leu.2404167. Leukemia. 2006. PMID: 16525497

5

Growth suppression and apoptosis induction in synovial sarcoma cell lines by a novel NF-kappaB inhibitor, dehydroxymethylepoxyquinomicin (DHMEQ).

Horiuchi K, Morioka H, Nishimoto K, Suzuki Y, Susa M, Nakayama R, Kawai A, Sonobe H, Takaishi H, Ozaki T, Yabe H, Umezawa K, Toyama Y. Horiuchi K, et al. Among authors: umezawa k. Cancer Lett. 2008 Dec 18;272(2):336-44. doi: 10.1016/j.canlet.2008.07.021. Epub 2008 Aug 28. Cancer Lett. 2008. PMID: 18760530

6

IkappaBalpha independent induction of NF-kappaB and its inhibition by DHMEQ in Hodgkin/Reed-Sternberg cells.

Watanabe M, Dewan MZ, Taira M, Shoda M, Honda M, Sata T, Higashihara M, Kadin ME, Watanabe T, Yamamoto N, Umezawa K, Horie R. Watanabe M, et al. Among authors: umezawa k. Lab Invest. 2007 Apr;87(4):372-82. doi: 10.1038/labinvest.3700528. Epub 2007 Feb 19. Lab Invest. 2007. PMID: 17310217 Free article.

7

Dehydroxymethylepoxyquinomicin (DHMEQ) therapy reduces tumor formation in mice inoculated with tax-deficient adult T-cell leukemia-derived cell lines.

Ohsugi T, Kumasaka T, Okada S, Ishida T, Yamaguchi K, Horie R, Watanabe T, Umezawa K. Ohsugi T, et al. Among authors: umezawa k. Cancer Lett. 2007 Nov 18;257(2):206-15. doi: 10.1016/j.canlet.2007.07.017. Epub 2007 Aug 30. Cancer Lett. 2007. PMID: 17764832

8

In vivo antitumor activity of the NF-kappaB inhibitor dehydroxymethylepoxyquinomicin in a mouse model of adult T-cell leukemia.

Ohsugi T, Horie R, Kumasaka T, Ishida A, Ishida T, Yamaguchi K, Watanabe T, Umezawa K, Urano T. Ohsugi T, et al. Among authors: umezawa k. Carcinogenesis. 2005 Aug;26(8):1382-8. doi: 10.1093/carcin/bgi095. Epub 2005 Apr 14. Carcinogenesis. 2005. PMID: 15831528

9

Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo.

Matsumoto G, Namekawa J, Muta M, Nakamura T, Bando H, Tohyama K, Toi M, Umezawa K. Matsumoto G, et al. Among authors: umezawa k. Clin Cancer Res. 2005 Feb 1;11(3):1287-93. Clin Cancer Res. 2005. PMID: 15709200

10

Induction of thyroid cancer cell apoptosis by a novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin.

Starenki DV, Namba H, Saenko VA, Ohtsuru A, Maeda S, Umezawa K, Yamashita S. Starenki DV, et al. Among authors: umezawa k. Clin Cancer Res. 2004 Oct 15;10(20):6821-9. doi: 10.1158/1078-0432.CCR-04-0463. Clin Cancer Res. 2004. PMID: 15501958

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