Kohl TM - Search Results

1

The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice.

Schessl C, Rawat VP, Cusan M, Deshpande A, Kohl TM, Rosten PM, Spiekermann K, Humphries RK, Schnittger S, Kern W, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M, Buske C. Schessl C, et al. Among authors: kohl tm. J Clin Invest. 2005 Aug;115(8):2159-68. doi: 10.1172/JCI24225. Epub 2005 Jul 14. J Clin Invest. 2005. PMID: 16025155 Free PMC article.

2

BH3 mimetic ABT-737 neutralizes resistance to FLT3 inhibitor treatment mediated by FLT3-independent expression of BCL2 in primary AML blasts.

Kohl TM, Hellinger C, Ahmed F, Buske C, Hiddemann W, Bohlander SK, Spiekermann K. Kohl TM, et al. Leukemia. 2007 Aug;21(8):1763-72. doi: 10.1038/sj.leu.2404776. Epub 2007 Jun 7. Leukemia. 2007. PMID: 17554384

3

KIT exon 8 mutations associated with core-binding factor (CBF)-acute myeloid leukemia (AML) cause hyperactivation of the receptor in response to stem cell factor.

Kohl TM, Schnittger S, Ellwart JW, Hiddemann W, Spiekermann K. Kohl TM, et al. Blood. 2005 Apr 15;105(8):3319-21. doi: 10.1182/blood-2004-06-2068. Epub 2004 Dec 23. Blood. 2005. PMID: 15618474 Free article.

4

KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival.

Schnittger S, Kohl TM, Haferlach T, Kern W, Hiddemann W, Spiekermann K, Schoch C. Schnittger S, et al. Among authors: kohl tm. Blood. 2006 Mar 1;107(5):1791-9. doi: 10.1182/blood-2005-04-1466. Epub 2005 Oct 27. Blood. 2006. PMID: 16254134 Free article.

5

Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD-transformed hematopoietic cells.

Bagrintseva K, Schwab R, Kohl TM, Schnittger S, Eichenlaub S, Ellwart JW, Hiddemann W, Spiekermann K. Bagrintseva K, et al. Among authors: kohl tm. Blood. 2004 Mar 15;103(6):2266-75. doi: 10.1182/blood-2003-05-1653. Epub 2003 Nov 6. Blood. 2004. PMID: 14604974 Free article.

6

D324N single-nucleotide polymorphism in the FLT3 gene is associated with higher risk of myeloid leukemias.

Schnittger S, Kohl TM, Leopold N, Schoch C, Wichmann HE, Kern W, Lohse P, Hiddemann W, Haferlach T, Spiekermann K. Schnittger S, et al. Among authors: kohl tm. Genes Chromosomes Cancer. 2006 Apr;45(4):332-7. doi: 10.1002/gcc.20294. Genes Chromosomes Cancer. 2006. PMID: 16320249

7

Transformation by oncogenic mutants and ligand-dependent activation of FLT3 wild-type requires the tyrosine residues 589 and 591.

Vempati S, Reindl C, Wolf U, Kern R, Petropoulos K, Naidu VM, Buske C, Hiddemann W, Kohl TM, Spiekermann K. Vempati S, et al. Among authors: kohl tm. Clin Cancer Res. 2008 Jul 15;14(14):4437-45. doi: 10.1158/1078-0432.CCR-07-1873. Clin Cancer Res. 2008. PMID: 18628457

8

Axial tubule junctions control rapid calcium signaling in atria.

Brandenburg S, Kohl T, Williams GS, Gusev K, Wagner E, Rog-Zielinska EA, Hebisch E, Dura M, Didié M, Gotthardt M, Nikolaev VO, Hasenfuss G, Kohl P, Ward CW, Lederer WJ, Lehnart SE. Brandenburg S, et al. J Clin Invest. 2016 Oct 3;126(10):3999-4015. doi: 10.1172/JCI88241. Epub 2016 Sep 19. J Clin Invest. 2016. PMID: 27643434 Free PMC article.

9

Analysis of tubular membrane networks in cardiac myocytes from atria and ventricles.

Wagner E, Brandenburg S, Kohl T, Lehnart SE. Wagner E, et al. J Vis Exp. 2014 Oct 15;(92):e51823. doi: 10.3791/51823. J Vis Exp. 2014. PMID: 25350293 Free PMC article.

10

Superresolution modeling of calcium release in the heart.

Walker MA, Williams GSB, Kohl T, Lehnart SE, Jafri MS, Greenstein JL, Lederer WJ, Winslow RL. Walker MA, et al. Biophys J. 2014 Dec 16;107(12):3018-3029. doi: 10.1016/j.bpj.2014.11.003. Biophys J. 2014. PMID: 25517166 Free PMC article.

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