Esposito L - Search Results

1

High beta-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease.

Rockenstein E, Mante M, Alford M, Adame A, Crews L, Hashimoto M, Esposito L, Mucke L, Masliah E. Rockenstein E, et al. Among authors: esposito l. J Biol Chem. 2005 Sep 23;280(38):32957-67. doi: 10.1074/jbc.M507016200. Epub 2005 Jul 15. J Biol Chem. 2005. PMID: 16027115 Free article.

2

Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells.

Esposito L, Gan L, Yu GQ, Essrich C, Mucke L. Esposito L, et al. J Neurochem. 2004 Dec;91(6):1260-74. doi: 10.1111/j.1471-4159.2004.02816.x. J Neurochem. 2004. PMID: 15584903 Free article.

3

Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice.

Esposito L, Raber J, Kekonius L, Yan F, Yu GQ, Bien-Ly N, Puoliväli J, Scearce-Levie K, Masliah E, Mucke L. Esposito L, et al. J Neurosci. 2006 May 10;26(19):5167-79. doi: 10.1523/JNEUROSCI.0482-06.2006. J Neurosci. 2006. PMID: 16687508 Free PMC article.

4

Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease.

Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Sun B, Chen J, Wang X, Yu G, Esposito L, Mucke L, Gan L. Mueller-Steiner S, et al. Among authors: esposito l. Neuron. 2006 Sep 21;51(6):703-14. doi: 10.1016/j.neuron.2006.07.027. Neuron. 2006. PMID: 16982417 Free article.

5

Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology.

Tesseur I, Zou K, Esposito L, Bard F, Berber E, Can JV, Lin AH, Crews L, Tremblay P, Mathews P, Mucke L, Masliah E, Wyss-Coray T. Tesseur I, et al. Among authors: esposito l. J Clin Invest. 2006 Nov;116(11):3060-9. doi: 10.1172/JCI27341. J Clin Invest. 2006. PMID: 17080199 Free PMC article.

6

Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation.

Cheng IH, Palop JJ, Esposito LA, Bien-Ly N, Yan F, Mucke L. Cheng IH, et al. Among authors: esposito la. Nat Med. 2004 Nov;10(11):1190-2. doi: 10.1038/nm1123. Epub 2004 Oct 24. Nat Med. 2004. PMID: 15502844

7

Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.

Meilandt WJ, Cisse M, Ho K, Wu T, Esposito LA, Scearce-Levie K, Cheng IH, Yu GQ, Mucke L. Meilandt WJ, et al. Among authors: esposito la. J Neurosci. 2009 Feb 18;29(7):1977-86. doi: 10.1523/JNEUROSCI.2984-08.2009. J Neurosci. 2009. PMID: 19228952 Free PMC article.

8

Measuring APP carboxy-terminal fragments.

Esposito LA. Esposito LA. Methods Mol Biol. 2011;670:71-84. doi: 10.1007/978-1-60761-744-0_6. Methods Mol Biol. 2011. PMID: 20967584

9

Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity.

Lee HP, Pancholi N, Esposito L, Previll LA, Wang X, Zhu X, Smith MA, Lee HG. Lee HP, et al. Among authors: esposito l. PLoS One. 2012;7(1):e28033. doi: 10.1371/journal.pone.0028033. Epub 2012 Jan 19. PLoS One. 2012. PMID: 22276093 Free PMC article.

10

Enhancer viruses for combinatorial cell-subclass-specific labeling.

Graybuck LT, Daigle TL, Sedeño-Cortés AE, Walker M, Kalmbach B, Lenz GH, Morin E, Nguyen TN, Garren E, Bendrick JL, Kim TK, Zhou T, Mortrud M, Yao S, Siverts LA, Larsen R, Gore BB, Szelenyi ER, Trader C, Balaram P, van Velthoven CTJ, Chiang M, Mich JK, Dee N, Goldy J, Cetin AH, Smith K, Way SW, Esposito L, Yao Z, Gradinaru V, Sunkin SM, Lein E, Levi BP, Ting JT, Zeng H, Tasic B. Graybuck LT, et al. Among authors: esposito l. Neuron. 2021 May 5;109(9):1449-1464.e13. doi: 10.1016/j.neuron.2021.03.011. Epub 2021 Mar 30. Neuron. 2021. PMID: 33789083 Free PMC article.

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