Heparin-binding sites in granulocyte-macrophage colony-stimulating factor. Localization and regulation by histidine ionization.
Sebollela A, Cagliari TC, Limaverde GS, Chapeaurouge A, Sorgine MH, Coelho-Sampaio T, Ramos CH, Ferreira ST.
Sebollela A, et al.
J Biol Chem. 2005 Sep 9;280(36):31949-56. doi: 10.1074/jbc.M505314200. Epub 2005 Jul 15.
J Biol Chem. 2005.
PMID: 16027123
Free article.
We have proposed previously that helix C, one of the four alpha-helices of human GM-CSF (hGM-CSF), contains a GAG-binding site in which positively charged residues are spatially positioned for interaction with the sulfate moieties of the GAGs (Wettreich, A., Sebo …
We have proposed previously that helix C, one of the four alpha-helices of human GM-CSF (hGM-CSF), contains a GAG-binding site in whi …