Najajreh Y - Search Results

1

Preparation, cytotoxicity and interactions with nucleophiles of three isomeric transplatinum complexes containing methylpiperidine ligands.

Jawbry S, Freikman I, Najajreh Y, Perez JM, Gibson D. Jawbry S, et al. Among authors: najajreh y. J Inorg Biochem. 2005 Oct;99(10):1983-91. doi: 10.1016/j.jinorgbio.2005.06.011. J Inorg Biochem. 2005. PMID: 16054219

2

Interactions of cisplatin and transplatin with proteins. Comparison of binding kinetics, binding sites and reactivity of the Pt-protein adducts of cisplatin and transplatin towards biological nucleophiles.

Peleg-Shulman T, Najajreh Y, Gibson D. Peleg-Shulman T, et al. Among authors: najajreh y. J Inorg Biochem. 2002 Jul 25;91(1):306-11. doi: 10.1016/s0162-0134(02)00362-8. J Inorg Biochem. 2002. PMID: 12121789

3

Novel soluble cationic trans-diaminedichloroplatinum(II) complexes that are active against cisplatin resistant ovarian cancer cell lines.

Najajreh Y, Perez JM, Navarro-Ranninger C, Gibson D. Najajreh Y, et al. J Med Chem. 2002 Nov 21;45(24):5189-95. doi: 10.1021/jm0201969. J Med Chem. 2002. PMID: 12431046

4

Cationic nonsymmetric transplatinum complexes with piperidinopiperidine ligands. Preparation, characterization, in vitro cytotoxicity, in vivo toxicity, and anticancer efficacy studies.

Najajreh Y, Khazanov E, Jawbry S, Ardeli-Tzaraf Y, Perez JM, Kasparkova J, Brabec V, Barenholz Y, Gibson D. Najajreh Y, et al. J Med Chem. 2006 Jul 27;49(15):4665-73. doi: 10.1021/jm060237r. J Med Chem. 2006. PMID: 16854072

5

Interactions of platinum complexes containing cationic, bicyclic, nonplanar piperidinopiperidine ligands with biological nucleophiles.

Najajreh Y, Ardeli-Tzaraf Y, Kasparkova J, Heringova P, Prilutski D, Balter L, Jawbry S, Khazanov E, Perez JM, Barenholz Y, Brabec V, Gibson D. Najajreh Y, et al. J Med Chem. 2006 Jul 27;49(15):4674-83. doi: 10.1021/jm060238j. J Med Chem. 2006. PMID: 16854073

6

Novel apoptosis-inducing trans-platinum piperidine derivatives: synthesis and biological characterization.

Khazanov E, Barenholz Y, Gibson D, Najajreh Y. Khazanov E, et al. Among authors: najajreh y. J Med Chem. 2002 Nov 21;45(24):5196-204. doi: 10.1021/jm020817y. J Med Chem. 2002. PMID: 12431047

7

Ligand effects on the binding of cis- and trans-[PtCl(2)Am(1)Am(2)] to proteins.

Najajreh Y, Peleg-Shulman T, Moshel O, Farrell N, Gibson D. Najajreh Y, et al. J Biol Inorg Chem. 2003 Jan;8(1-2):167-75. doi: 10.1007/s00775-002-0402-y. Epub 2002 Sep 25. J Biol Inorg Chem. 2003. PMID: 12459912

8

DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines.

Kasparkova J, Marini V, Najajreh Y, Gibson D, Brabec V. Kasparkova J, et al. Among authors: najajreh y. Biochemistry. 2003 May 27;42(20):6321-32. doi: 10.1021/bi0342315. Biochemistry. 2003. PMID: 12755637

9

Water soluble cationic trans-platinum complexes which induce programmed cell death in the protozoan parasite Leishmania infantum.

Nguewa PA, Fuertes MA, Iborra S, Najajreh Y, Gibson D, Martínez E, Alonso C, Pérez JM. Nguewa PA, et al. Among authors: najajreh y. J Inorg Biochem. 2005 Mar;99(3):727-36. doi: 10.1016/j.jinorgbio.2004.12.008. Epub 2005 Jan 1. J Inorg Biochem. 2005. PMID: 15708793

10

Structure and unique interactions with DNA of a cationic trans-platinum complex with the nonplanar bicyclic piperidinopiperidine ligand.

Najajreh Y, Prilutski D, Ardeli-Tzaraf Y, Perez JM, Khazanov E, Barenholz Y, Kasparkova J, Brabec V, Gibson D. Najajreh Y, et al. Angew Chem Int Ed Engl. 2005 May 6;44(19):2885-7. doi: 10.1002/anie.200462389. Angew Chem Int Ed Engl. 2005. PMID: 15822135 No abstract available.

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