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Role of phosphorylation and basic residues in the catalytic domain of cytosolic phospholipase A2alpha in regulating interfacial kinetics and binding and cellular function.
Tucker DE, Ghosh M, Ghomashchi F, Loper R, Suram S, John BS, Girotti M, Bollinger JG, Gelb MH, Leslie CC. Tucker DE, et al. Among authors: ghomashchi f. J Biol Chem. 2009 Apr 3;284(14):9596-611. doi: 10.1074/jbc.M807299200. Epub 2009 Jan 28. J Biol Chem. 2009. PMID: 19176526 Free PMC article.
Arachidonic acid release from mammalian cells transfected with human groups IIA and X secreted phospholipase A(2) occurs predominantly during the secretory process and with the involvement of cytosolic phospholipase A(2)-alpha.
Mounier CM, Ghomashchi F, Lindsay MR, James S, Singer AG, Parton RG, Gelb MH. Mounier CM, et al. Among authors: ghomashchi f. J Biol Chem. 2004 Jun 11;279(24):25024-38. doi: 10.1074/jbc.M313019200. Epub 2004 Mar 8. J Biol Chem. 2004. PMID: 15007070 Free article.
Cytosolic phospholipase A2-alpha is necessary for platelet-activating factor biosynthesis, efficient neutrophil-mediated bacterial killing, and the innate immune response to pulmonary infection: cPLA2-alpha does not regulate neutrophil NADPH oxidase activity.
Rubin BB, Downey GP, Koh A, Degousee N, Ghomashchi F, Nallan L, Stefanski E, Harkin DW, Sun C, Smart BP, Lindsay TF, Cherepanov V, Vachon E, Kelvin D, Sadilek M, Brown GE, Yaffe MB, Plumb J, Grinstein S, Glogauer M, Gelb MH. Rubin BB, et al. Among authors: ghomashchi f. J Biol Chem. 2005 Mar 4;280(9):7519-29. doi: 10.1074/jbc.M407438200. Epub 2004 Oct 8. J Biol Chem. 2005. PMID: 15475363 Free PMC article.
59 results