Shaffer D - Search Results

1

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.

Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP. Chen Z, et al. Among authors: shaffer d. Nature. 2005 Aug 4;436(7051):725-30. doi: 10.1038/nature03918. Nature. 2005. PMID: 16079851 Free PMC article.

2

Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.

Wang G, Lunardi A, Zhang J, Chen Z, Ala U, Webster KA, Tay Y, Gonzalez-Billalabeitia E, Egia A, Shaffer DR, Carver B, Liu XS, Taulli R, Kuo WP, Nardella C, Signoretti S, Cordon-Cardo C, Gerald WL, Pandolfi PP. Wang G, et al. Nat Genet. 2013 Jul;45(7):739-746. doi: 10.1038/ng.2654. Epub 2013 Jun 2. Nat Genet. 2013. PMID: 23727861 Free PMC article.

3

Prostate cancer: a dynamic illness with shifting targets.

Shaffer DR, Scher HI. Shaffer DR, et al. Lancet Oncol. 2003 Jul;4(7):407-14. doi: 10.1016/s1470-2045(03)01138-0. Lancet Oncol. 2003. PMID: 12850191 Review.

4

Breaking the rules of cancer.

Shaffer DR, Pandolfi PP. Shaffer DR, et al. Nat Med. 2006 Jan;12(1):14-5. doi: 10.1038/nm0106-14. Nat Med. 2006. PMID: 16397543 No abstract available.

5

p27 deficiency desensitizes Rb-/- cells to signals that trigger apoptosis during pituitary tumor development.

Carneiro C, Jiao MS, Hu M, Shaffer D, Park M, Pandolfi PP, Cordon-Cardo C, Koff A. Carneiro C, et al. Among authors: shaffer d. Oncogene. 2003 Jan 23;22(3):361-9. doi: 10.1038/sj.onc.1206163. Oncogene. 2003. PMID: 12545157

6

Critical function for ADAM9 in mouse prostate cancer.

Peduto L, Reuter VE, Shaffer DR, Scher HI, Blobel CP. Peduto L, et al. Cancer Res. 2005 Oct 15;65(20):9312-9. doi: 10.1158/0008-5472.CAN-05-1063. Cancer Res. 2005. PMID: 16230393

7

ADAM12 is highly expressed in carcinoma-associated stroma and is required for mouse prostate tumor progression.

Peduto L, Reuter VE, Sehara-Fujisawa A, Shaffer DR, Scher HI, Blobel CP. Peduto L, et al. Among authors: shaffer dr. Oncogene. 2006 Aug 31;25(39):5462-6. doi: 10.1038/sj.onc.1209536. Epub 2006 Apr 10. Oncogene. 2006. PMID: 16607276

8

Evidence for a p27 tumor suppressive function independent of its role regulating cell proliferation in the prostate.

Shaffer DR, Viale A, Ishiwata R, Leversha M, Olgac S, Manova K, Satagopan J, Scher H, Koff A. Shaffer DR, et al. Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):210-5. doi: 10.1073/pnas.0407362102. Epub 2004 Dec 22. Proc Natl Acad Sci U S A. 2005. PMID: 15615849 Free PMC article.

9

Differential exoprotease activities confer tumor-specific serum peptidome patterns.

Villanueva J, Shaffer DR, Philip J, Chaparro CA, Erdjument-Bromage H, Olshen AB, Fleisher M, Lilja H, Brogi E, Boyd J, Sanchez-Carbayo M, Holland EC, Cordon-Cardo C, Scher HI, Tempst P. Villanueva J, et al. J Clin Invest. 2006 Jan;116(1):271-84. doi: 10.1172/JCI26022. J Clin Invest. 2006. PMID: 16395409 Free PMC article.

10

Everolimus combined with gefitinib in patients with metastatic castration-resistant prostate cancer: Phase 1/2 results and signaling pathway implications.

Rathkopf DE, Larson SM, Anand A, Morris MJ, Slovin SF, Shaffer DR, Heller G, Carver B, Rosen N, Scher HI. Rathkopf DE, et al. Cancer. 2015 Nov 1;121(21):3853-61. doi: 10.1002/cncr.29578. Epub 2015 Jul 15. Cancer. 2015. PMID: 26178426 Free PMC article. Clinical Trial.

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