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Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2: inverse correlation during progression from gastric/intestinal-mixed to complete intestinal metaplasia.
Tsukamoto T, Inada K, Tanaka H, Mizoshita T, Mihara M, Ushijima T, Yamamura Y, Nakamura S, Tatematsu M. Tsukamoto T, et al. Among authors: inada k. J Cancer Res Clin Oncol. 2004 Mar;130(3):135-45. doi: 10.1007/s00432-003-0519-6. Epub 2003 Dec 4. J Cancer Res Clin Oncol. 2004. PMID: 14655050
Immunohistochemically detectable Cdx2 is present in intestinal phenotypic elements in early gastric cancers of both differentiated and undifferentiated types, with no correlation to non-neoplastic surrounding mucosa.
Mizoshita T, Tsukamoto T, Inada K, Ogasawara N, Hirata A, Kato S, Joh T, Itoh M, Yamamura Y, Tatematsu M. Mizoshita T, et al. Among authors: inada k. Pathol Int. 2004 Jun;54(6):392-400. doi: 10.1111/j.1440-1827.2004.01647.x. Pathol Int. 2004. PMID: 15144397
791 results