Overkleeft HS - Search Results

1

Combinatorial discovery of new asymmetric cis platinum anticancer complexes is made possible with solid-phase synthetic methods.

van Zutphen S, Stone EA, van Rijt S, Robillard MS, van der Marel GA, Overkleeft HS, den Dulk H, Brouwer J, Reedijk J. van Zutphen S, et al. Among authors: overkleeft hs. J Inorg Biochem. 2005 Oct;99(10):2032-8. doi: 10.1016/j.jinorgbio.2005.06.033. J Inorg Biochem. 2005. PMID: 16099049

2

Extending solid-phase methods in inorganic synthesis: the first dinuclear platinum complex synthesised via the solid phase.

van Zutphen S, Robillard MS, van der Marel GA, Overkleeft HS, den Dulk H, Brouwer J, Reedijk J. van Zutphen S, et al. Among authors: overkleeft hs. Chem Commun (Camb). 2003 Mar 7;(5):634-5. doi: 10.1039/b212388f. Chem Commun (Camb). 2003. PMID: 12669861

3

Ph2SO/Tf2O: a powerful promotor system in chemoselective glycosylations using thioglycosides.

Codée JD, Litjens RE, den Heeten R, Overkleeft HS, van Boom JH, van der Marel GA. Codée JD, et al. Among authors: overkleeft hs. Org Lett. 2003 May 1;5(9):1519-22. doi: 10.1021/ol034312t. Org Lett. 2003. PMID: 12713313

4

Sequential one-pot glycosylations using 1-hydroxyl and 1-thiodonors.

Codée JD, van den Bos LJ, Litjens RE, Overkleeft HS, van Boom JH, van der Marel GA. Codée JD, et al. Among authors: overkleeft hs. Org Lett. 2003 May 29;5(11):1947-50. doi: 10.1021/ol034528v. Org Lett. 2003. PMID: 12762693

5

The beta-glucuronyl-based prodrug strategy allows for its application on beta-glucuronyl-platinum conjugates.

Tromp RA, van Boom SS, Marco Timmers C, van Zutphen S, van der Marel GA, Overkleeft HS, van Boom JH, Reedijk J. Tromp RA, et al. Among authors: overkleeft hs. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4273-6. doi: 10.1016/j.bmcl.2004.06.015. Bioorg Med Chem Lett. 2004. PMID: 15261285

6

Design, synthesis, and evaluation of sugar amino acid based inhibitors of protein prenyl transferases PFT and PGGT-1.

El Oualid F, Burm BE, Leroy IM, Cohen LH, van Boom JH, van den Elst H, Overkleeft HS, van der Marel GA, Overhand M. El Oualid F, et al. Among authors: overkleeft hs. J Med Chem. 2004 Jul 29;47(16):3920-3. doi: 10.1021/jm049927q. J Med Chem. 2004. PMID: 15267228

7

Alkylated sugar amino acids: a new entry toward highly functionalized dipeptide isosters.

Raunkjaer M, El Oualid F, van der Marel GA, Overkleeft HS, Overhand M. Raunkjaer M, et al. Among authors: overkleeft hs. Org Lett. 2004 Sep 2;6(18):3167-70. doi: 10.1021/ol048750r. Org Lett. 2004. PMID: 15330614

8

Synthesis and biological evaluation of lipophilic Ca(1)a(2)L analogues as potential bisubstrate inhibitors of protein:geranylgeranyl transferase-1.

El Oualid F, Baktawar J, Leroy IM, van den Elst H, Cohen LH, van der Marel GA, Overkleeft HS, Overhand M. El Oualid F, et al. Among authors: overkleeft hs. Bioorg Med Chem. 2005 Mar 1;13(5):1463-75. doi: 10.1016/j.bmc.2004.12.035. Bioorg Med Chem. 2005. PMID: 15698762

9

Probing the potential of platinum(II) complexes for the inhibition of thiol-dependent enzymatic activity.

van Zutphen S, Kraus M, Driessen C, van der Marel GA, Overkleeft HS, Reedijk J. van Zutphen S, et al. Among authors: overkleeft hs. J Inorg Biochem. 2005 Jun;99(6):1384-9. doi: 10.1016/j.jinorgbio.2005.03.014. J Inorg Biochem. 2005. PMID: 15869797

10

A combinatorial approach toward the generation of ambiphilic peptide-based inhibitors of protein:geranylgeranyl transferase-1.

El Oualid F, van den Elst H, Leroy IM, Pieterman E, Cohen LH, Burm BE, Overkleeft HS, van der Marel GA, Overhand M. El Oualid F, et al. Among authors: overkleeft hs. J Comb Chem. 2005 Sep-Oct;7(5):703-13. doi: 10.1021/cc0500203. J Comb Chem. 2005. PMID: 16153065

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