Willson TM - Search Results

1

Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure.

Jaye MC, Krawiec JA, Campobasso N, Smallwood A, Qiu C, Lu Q, Kerrigan JJ, De Los Frailes Alvaro M, Laffitte B, Liu WS, Marino JP Jr, Meyer CR, Nichols JA, Parks DJ, Perez P, Sarov-Blat L, Seepersaud SD, Steplewski KM, Thompson SK, Wang P, Watson MA, Webb CL, Haigh D, Caravella JA, Macphee CH, Willson TM, Collins JL. Jaye MC, et al. Among authors: willson tm. J Med Chem. 2005 Aug 25;48(17):5419-22. doi: 10.1021/jm050532w. J Med Chem. 2005. PMID: 16107141

2

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma).

Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. Lehmann JM, et al. Among authors: willson tm. J Biol Chem. 1995 Jun 2;270(22):12953-6. doi: 10.1074/jbc.270.22.12953. J Biol Chem. 1995. PMID: 7768881 Free article.

3

3-[4-(1,2-Diphenylbut-1-enyl)phenyl]acrylic acid: a non-steroidal estrogen with functional selectivity for bone over uterus in rats.

Willson TM, Henke BR, Momtahen TM, Charifson PS, Batchelor KW, Lubahn DB, Moore LB, Oliver BB, Sauls HR, Triantafillou JA, et al. Willson TM, et al. J Med Chem. 1994 May 27;37(11):1550-2. doi: 10.1021/jm00037a002. J Med Chem. 1994. PMID: 8201587 No abstract available.

4

The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones.

Willson TM, Cobb JE, Cowan DJ, Wiethe RW, Correa ID, Prakash SR, Beck KD, Moore LB, Kliewer SA, Lehmann JM. Willson TM, et al. J Med Chem. 1996 Feb 2;39(3):665-8. doi: 10.1021/jm950395a. J Med Chem. 1996. PMID: 8576907 No abstract available.

5

3-(1H-indazol-3-ylmethyl)-1,5-benzodiazepines: CCK-A agonists that demonstrate oral activity as satiety agents.

Henke BR, Willson TM, Sugg EE, Croom DK, Dougherty RW Jr, Queen KL, Birkemo LS, Ervin GN, Grizzle MK, Johnson MF, James MK. Henke BR, et al. Among authors: willson tm. J Med Chem. 1996 Jul 5;39(14):2655-8. doi: 10.1021/jm960249k. J Med Chem. 1996. PMID: 8709093 No abstract available.

6

3-[2-(N-phenylacetamide)]-1,5-benzodiazepines: orally active, binding selective CCK-A agonists.

Willson TM, Henke BR, Momtahen TM, Myers PL, Sugg EE, Unwalla RJ, Croom DK, Dougherty RW, Grizzle MK, Johnson MF, Queen KL, Rimele TJ, Yingling JD, James MK. Willson TM, et al. J Med Chem. 1996 Jul 19;39(15):3030-4. doi: 10.1021/jm960205b. J Med Chem. 1996. PMID: 8709137

7

Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity (II): Optimization of the C3 amino substituent.

Hirst GC, Aquino C, Birkemo L, Croom DK, Dezube M, Dougherty RW Jr, Ervin GN, Grizzle MK, Henke B, James MK, Johnson MF, Momtahen T, Queen KL, Sherrill RG, Szewczyk J, Willson TM, Sugg EE. Hirst GC, et al. Among authors: willson tm. J Med Chem. 1996 Dec 20;39(26):5236-45. doi: 10.1021/jm9601664. J Med Chem. 1996. PMID: 8978852

8

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway.

Lehmann JM, Kliewer SA, Moore LB, Smith-Oliver TA, Oliver BB, Su JL, Sundseth SS, Winegar DA, Blanchard DE, Spencer TA, Willson TM. Lehmann JM, et al. Among authors: willson tm. J Biol Chem. 1997 Feb 7;272(6):3137-40. doi: 10.1074/jbc.272.6.3137. J Biol Chem. 1997. PMID: 9013544 Free article.

9

Optimization of 3-(1H-indazol-3-ylmethyl)-1,5-benzodiazepines as potent, orally active CCK-A agonists.

Henke BR, Aquino CJ, Birkemo LS, Croom DK, Dougherty RW Jr, Ervin GN, Grizzle MK, Hirst GC, James MK, Johnson MF, Queen KL, Sherrill RG, Sugg EE, Suh EM, Szewczyk JW, Unwalla RJ, Yingling J, Willson TM. Henke BR, et al. Among authors: willson tm. J Med Chem. 1997 Aug 15;40(17):2706-25. doi: 10.1021/jm970265x. J Med Chem. 1997. PMID: 9276016

10

Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library.

Brown PJ, Smith-Oliver TA, Charifson PS, Tomkinson NC, Fivush AM, Sternbach DD, Wade LE, Orband-Miller L, Parks DJ, Blanchard SG, Kliewer SA, Lehmann JM, Willson TM. Brown PJ, et al. Among authors: willson tm. Chem Biol. 1997 Dec;4(12):909-18. doi: 10.1016/s1074-5521(97)90299-4. Chem Biol. 1997. PMID: 9427656

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

236 results

Search Page

Filters