Chang NS - Search Results

1

WOX1 is essential for UVB irradiation-induced apoptosis and down-regulated via translational blockade in UVB-induced cutaneous squamous cell carcinoma in vivo.

Lai FJ, Cheng CL, Chen ST, Wu CH, Hsu LJ, Lee JY, Chao SC, Sheen MC, Shen CL, Chang NS, Sheu HM. Lai FJ, et al. Among authors: chang ns. Clin Cancer Res. 2005 Aug 15;11(16):5769-77. doi: 10.1158/1078-0432.CCR-04-2274. Clin Cancer Res. 2005. PMID: 16115915

2

Molecular mechanisms underlying WOX1 activation during apoptotic and stress responses.

Chang NS, Doherty J, Ensign A, Lewis J, Heath J, Schultz L, Chen ST, Oppermann U. Chang NS, et al. Biochem Pharmacol. 2003 Oct 15;66(8):1347-54. doi: 10.1016/s0006-2952(03)00484-2. Biochem Pharmacol. 2003. PMID: 14555208

3

Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease.

Sze CI, Su M, Pugazhenthi S, Jambal P, Hsu LJ, Heath J, Schultz L, Chang NS. Sze CI, et al. Among authors: chang ns. J Biol Chem. 2004 Jul 16;279(29):30498-506. doi: 10.1074/jbc.M401399200. Epub 2004 May 4. J Biol Chem. 2004. PMID: 15126504 Free article.

4

17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo.

Chang NS, Schultz L, Hsu LJ, Lewis J, Su M, Sze CI. Chang NS, et al. Oncogene. 2005 Jan 20;24(4):714-23. doi: 10.1038/sj.onc.1208124. Oncogene. 2005. PMID: 15580310

5

Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1.

Hsu LJ, Schultz L, Mattison J, Lin YS, Chang NS. Hsu LJ, et al. Among authors: chang ns. Biochem Biophys Res Commun. 2005 Feb 11;327(2):415-23. doi: 10.1016/j.bbrc.2004.12.025. Biochem Biophys Res Commun. 2005. PMID: 15629131

6

WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53.

Chang NS, Doherty J, Ensign A, Schultz L, Hsu LJ, Hong Q. Chang NS, et al. J Biol Chem. 2005 Dec 30;280(52):43100-8. doi: 10.1074/jbc.M505590200. Epub 2005 Oct 11. J Biol Chem. 2005. PMID: 16219768 Free article.

7

WW domain-containing oxidoreductase: a candidate tumor suppressor.

Chang NS, Hsu LJ, Lin YS, Lai FJ, Sheu HM. Chang NS, et al. Trends Mol Med. 2007 Jan;13(1):12-22. doi: 10.1016/j.molmed.2006.11.006. Epub 2006 Dec 4. Trends Mol Med. 2007. PMID: 17142102

8

Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response.

Hong Q, Hsu LJ, Schultz L, Pratt N, Mattison J, Chang NS. Hong Q, et al. Among authors: chang ns. BMC Mol Biol. 2007 Jun 13;8:50. doi: 10.1186/1471-2199-8-50. BMC Mol Biol. 2007. PMID: 17567906 Free PMC article.

9

MPP+-induced neuronal death in rats involves tyrosine 33 phosphorylation of WW domain-containing oxidoreductase WOX1.

Lo CP, Hsu LJ, Li MY, Hsu SY, Chuang JI, Tsai MS, Lin SR, Chang NS, Chen ST. Lo CP, et al. Among authors: chang ns. Eur J Neurosci. 2008 Apr;27(7):1634-46. doi: 10.1111/j.1460-9568.2008.06139.x. Epub 2008 Mar 26. Eur J Neurosci. 2008. PMID: 18371080

10

Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria.

Hsu LJ, Hong Q, Schultz L, Kuo E, Lin SR, Lee MH, Lin YS, Chang NS. Hsu LJ, et al. Among authors: chang ns. Cell Signal. 2008 Jul;20(7):1303-12. doi: 10.1016/j.cellsig.2008.02.018. Epub 2008 Mar 4. Cell Signal. 2008. PMID: 18403180

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