Bowers KE - Search Results

1

A continuous fluorescent assay for protein prenyltransferases measuring diphosphate release.

Pais JE, Bowers KE, Stoddard AK, Fierke CA. Pais JE, et al. Among authors: bowers ke. Anal Biochem. 2005 Oct 15;345(2):302-11. doi: 10.1016/j.ab.2005.07.040. Anal Biochem. 2005. PMID: 16143290

2

Kinetic studies of protein farnesyltransferase mutants establish active substrate conformation.

Pickett JS, Bowers KE, Hartman HL, Fu HW, Embry AC, Casey PJ, Fierke CA. Pickett JS, et al. Among authors: bowers ke. Biochemistry. 2003 Aug 19;42(32):9741-8. doi: 10.1021/bi0346852. Biochemistry. 2003. PMID: 12911316

3

Positively charged side chains in protein farnesyltransferase enhance catalysis by stabilizing the formation of the diphosphate leaving group.

Bowers KE, Fierke CA. Bowers KE, et al. Biochemistry. 2004 May 11;43(18):5256-65. doi: 10.1021/bi049822p. Biochemistry. 2004. PMID: 15122891

4

Mutagenesis studies of protein farnesyltransferase implicate aspartate beta 352 as a magnesium ligand.

Pickett JS, Bowers KE, Fierke CA. Pickett JS, et al. Among authors: bowers ke. J Biol Chem. 2003 Dec 19;278(51):51243-50. doi: 10.1074/jbc.M309226200. Epub 2003 Oct 7. J Biol Chem. 2003. PMID: 14532266 Free article.

5

Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium.

Hartman HL, Bowers KE, Fierke CA. Hartman HL, et al. Among authors: bowers ke. J Biol Chem. 2004 Jul 16;279(29):30546-53. doi: 10.1074/jbc.M403469200. Epub 2004 May 5. J Biol Chem. 2004. PMID: 15131129 Free article.

6

Measurement of the alpha-secondary kinetic isotope effect for the reaction catalyzed by mammalian protein farnesyltransferase.

Pais JE, Bowers KE, Fierke CA. Pais JE, et al. Among authors: bowers ke. J Am Chem Soc. 2006 Nov 29;128(47):15086-7. doi: 10.1021/ja065838m. J Am Chem Soc. 2006. PMID: 17117849

7

Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases.

Shao F, Vacratsis PO, Bao Z, Bowers KE, Fierke CA, Dixon JE. Shao F, et al. Among authors: bowers ke. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):904-9. doi: 10.1073/pnas.252770599. Epub 2003 Jan 21. Proc Natl Acad Sci U S A. 2003. PMID: 12538863 Free PMC article.

8

Photoaffinity analogues of farnesyl pyrophosphate transferable by protein farnesyl transferase.

Chehade KA, Kiegiel K, Isaacs RJ, Pickett JS, Bowers KE, Fierke CA, Andres DA, Spielmann HP. Chehade KA, et al. Among authors: bowers ke. J Am Chem Soc. 2002 Jul 17;124(28):8206-19. doi: 10.1021/ja0124717. J Am Chem Soc. 2002. PMID: 12105898

9

Folding mechanism of the alpha-subunit of tryptophan synthase, an alpha/beta barrel protein: global analysis highlights the interconversion of multiple native, intermediate, and unfolded forms through parallel channels.

Bilsel O, Zitzewitz JA, Bowers KE, Matthews CR. Bilsel O, et al. Among authors: bowers ke. Biochemistry. 1999 Jan 19;38(3):1018-29. doi: 10.1021/bi982365q. Biochemistry. 1999. PMID: 9893998

10

Probing minimal independent folding units in dihydrofolate reductase by molecular dissection.

Gegg CV, Bowers KE, Matthews CR. Gegg CV, et al. Among authors: bowers ke. Protein Sci. 1997 Sep;6(9):1885-92. doi: 10.1002/pro.5560060909. Protein Sci. 1997. PMID: 9300488 Free PMC article.

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