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Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19).
Hirose K, Inukai T, Kikuchi J, Furukawa Y, Ikawa T, Kawamoto H, Oram SH, Göttgens B, Kiyokawa N, Miyagawa Y, Okita H, Akahane K, Zhang X, Kuroda I, Honna H, Kagami K, Goi K, Kurosawa H, Look AT, Matsui H, Inaba T, Sugita K. Hirose K, et al. Among authors: zhang x. Blood. 2010 Aug 12;116(6):962-70. doi: 10.1182/blood-2009-09-244673. Epub 2010 Jun 2. Blood. 2010. PMID: 20519628 Free article.
Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors.
Zhang X, Inukai T, Hirose K, Akahane K, Kuroda I, Honna-Oshiro H, Kagami K, Goi K, Nakamura K, Kobayashi M, Endo M, Yagita H, Kurosawa H, Thomas Look A, Honda H, Inaba T, Nakazawa S, Sugita K. Zhang X, et al. Leukemia. 2012 Dec;26(12):2483-93. doi: 10.1038/leu.2012.139. Epub 2012 May 30. Leukemia. 2012. PMID: 22743623
Resistance of infant leukemia with MLL rearrangement to tumor necrosis factor-related apoptosis-inducing ligand: a possible mechanism for poor sensitivity to antitumor immunity.
Inukai T, Zhang X, Goto M, Hirose K, Uno K, Akahane K, Nemoto A, Goi K, Sato H, Takahashi K, Honna H, Kagami K, Nakamoto K, Yagita H, Okumura K, Koyama-Okazaki T, Nakazawa S, Sugita K. Inukai T, et al. Among authors: zhang x. Leukemia. 2006 Dec;20(12):2119-29. doi: 10.1038/sj.leu.2404429. Epub 2006 Oct 26. Leukemia. 2006. PMID: 17066095
Specific induction of CD33 expression by E2A-HLF: the first evidence for aberrant myeloid antigen expression in ALL by a fusion transcription factor.
Akahane K, Inukai T, Inaba T, Kurosawa H, Look AT, Kiyokawa N, Fujimoto J, Goto H, Endo M, Zhang X, Hirose K, Kuroda I, Honna H, Kagami K, Goi K, Nakazawa S, Sugita K. Akahane K, et al. Among authors: zhang x. Leukemia. 2010 Apr;24(4):865-9. doi: 10.1038/leu.2010.8. Epub 2010 Feb 11. Leukemia. 2010. PMID: 20147975 No abstract available.
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