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Multiple neurosteroid and cholesterol binding sites in voltage-dependent anion channel-1 determined by photo-affinity labeling.
Cheng WWL, Budelier MM, Sugasawa Y, Bergdoll L, Queralt-Martín M, Rosencrans W, Rostovtseva TK, Chen ZW, Abramson J, Krishnan K, Covey DF, Whitelegge JP, Evers AS. Cheng WWL, et al. Among authors: covey df. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct;1864(10):1269-1279. doi: 10.1016/j.bbalip.2019.06.004. Epub 2019 Jun 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31176038 Free PMC article.
Oxysterols are allosteric activators of the oncoprotein Smoothened.
Nachtergaele S, Mydock LK, Krishnan K, Rammohan J, Schlesinger PH, Covey DF, Rohatgi R. Nachtergaele S, et al. Among authors: covey df. Nat Chem Biol. 2012 Jan 8;8(2):211-20. doi: 10.1038/nchembio.765. Nat Chem Biol. 2012. PMID: 22231273 Free PMC article.
Structural design of intrinsically fluorescent oxysterols.
Nåbo LJ, Modzel M, Krishnan K, Covey DF, Fujiwara H, Ory DS, Szomek M, Khandelia H, Wüstner D, Kongsted J. Nåbo LJ, et al. Among authors: covey df. Chem Phys Lipids. 2018 May;212:26-34. doi: 10.1016/j.chemphyslip.2017.12.005. Epub 2017 Dec 26. Chem Phys Lipids. 2018. PMID: 29287905
Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α1β2γ2L GABA(A) Receptors.
Chakrabarti S, Qian M, Krishnan K, Covey DF, Mennerick S, Akk G. Chakrabarti S, et al. Among authors: covey df. Mol Pharmacol. 2016 Apr;89(4):399-406. doi: 10.1124/mol.115.102202. Epub 2016 Jan 14. Mol Pharmacol. 2016. PMID: 26769414 Free PMC article.
344 results