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A comparison of the cyclooxygenase inhibitor-NO donors (CINOD), NMI-1182 and AZD3582, using in vitro biochemical and pharmacological methods.
Young DV, Cochran ED, Dhawan V, Earl RA, Ellis JL, Garvey DS, Janero DR, Khanapure SP, Letts LG, Melim TL, Murty MG, Shumway MJ, Wey SJ, Zemtseva IS, Selig WM. Young DV, et al. Among authors: shumway mj. Biochem Pharmacol. 2005 Nov 1;70(9):1343-51. doi: 10.1016/j.bcp.2005.08.004. Biochem Pharmacol. 2005. PMID: 16168964
NMI-1182, a gastro-protective cyclo-oxygenase-inhibiting nitric oxide donor.
Ellis JL, Augustyniak ME, Cochran ED, Earl RA, Garvey DS, Gordon LJ, Janero DR, Khanapure SP, Letts LG, Melim TL, Murty MG, Schwalb DJ, Shumway MJ, Selig WM, Trocha AM, Young DV, Zemtseva IS. Ellis JL, et al. Among authors: shumway mj. Inflammopharmacology. 2005;12(5-6):521-34. doi: 10.1163/156856005774382661. Inflammopharmacology. 2005. PMID: 16259719
3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)(2-pyridyl) phenyl ketone as a potent and orally active cyclooxygenase-2 selective inhibitor: synthesis and biological evaluation.
Khanapure SP, Augustyniak ME, Earl RA, Garvey DS, Letts LG, Martino AM, Murty MG, Schwalb DJ, Shumway MJ, Trocha AM, Young DV, Zemtseva IS, Janero DR. Khanapure SP, et al. Among authors: shumway mj. J Med Chem. 2005 Jun 2;48(11):3930-4. doi: 10.1021/jm0582064. J Med Chem. 2005. PMID: 15916445