Linhart H - Search Results

1

Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis.

Yamada Y, Jackson-Grusby L, Linhart H, Meissner A, Eden A, Lin H, Jaenisch R. Yamada Y, et al. Among authors: linhart h. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13580-5. doi: 10.1073/pnas.0506612102. Epub 2005 Sep 8. Proc Natl Acad Sci U S A. 2005. PMID: 16174748 Free PMC article.

2

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing.

Linhart HG, Lin H, Yamada Y, Moran E, Steine EJ, Gokhale S, Lo G, Cantu E, Ehrich M, He T, Meissner A, Jaenisch R. Linhart HG, et al. Genes Dev. 2007 Dec 1;21(23):3110-22. doi: 10.1101/gad.1594007. Genes Dev. 2007. PMID: 18056424 Free PMC article.

3

Suppression of intestinal neoplasia by deletion of Dnmt3b.

Lin H, Yamada Y, Nguyen S, Linhart H, Jackson-Grusby L, Meissner A, Meletis K, Lo G, Jaenisch R. Lin H, et al. Among authors: linhart h. Mol Cell Biol. 2006 Apr;26(8):2976-83. doi: 10.1128/MCB.26.8.2976-2983.2006. Mol Cell Biol. 2006. PMID: 16581773 Free PMC article.

4

Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations.

Linhart HG, Troen A, Bell GW, Cantu E, Chao WH, Moran E, Steine E, He T, Jaenisch R. Linhart HG, et al. Gastroenterology. 2009 Jan;136(1):227-235.e3. doi: 10.1053/j.gastro.2008.10.016. Epub 2008 Oct 9. Gastroenterology. 2009. PMID: 18992744 Free PMC article.

5

Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer.

Steine EJ, Ehrich M, Bell GW, Raj A, Reddy S, van Oudenaarden A, Jaenisch R, Linhart HG. Steine EJ, et al. J Clin Invest. 2011 May;121(5):1748-52. doi: 10.1172/JCI43169. Epub 2011 Apr 1. J Clin Invest. 2011. PMID: 21490393 Free PMC article.

6

Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a.

Weis B, Schmidt J, Maamar H, Raj A, Lin H, Tóth C, Riedmann K, Raddatz G, Seitz HK, Ho AD, Lyko F, Linhart HG. Weis B, et al. Among authors: linhart hg. Oncogene. 2015 Apr 2;34(14):1822-30. doi: 10.1038/onc.2014.114. Epub 2014 May 19. Oncogene. 2015. PMID: 24837369

7

Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway.

Tomita H, Yamada Y, Oyama T, Hata K, Hirose Y, Hara A, Kunisada T, Sugiyama Y, Adachi Y, Linhart H, Mori H. Tomita H, et al. Among authors: linhart h. Cancer Res. 2007 May 1;67(9):4079-87. doi: 10.1158/0008-5472.CAN-06-4025. Cancer Res. 2007. PMID: 17483318

8

Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.

Kronenberg G, Harms C, Sobol RW, Cardozo-Pelaez F, Linhart H, Winter B, Balkaya M, Gertz K, Gay SB, Cox D, Eckart S, Ahmadi M, Juckel G, Kempermann G, Hellweg R, Sohr R, Hörtnagl H, Wilson SH, Jaenisch R, Endres M. Kronenberg G, et al. Among authors: linhart h. J Neurosci. 2008 Jul 9;28(28):7219-30. doi: 10.1523/JNEUROSCI.0940-08.2008. J Neurosci. 2008. PMID: 18614692 Free PMC article.

9

Cell-of-Origin DNA Methylation Signatures Are Maintained during Colorectal Carcinogenesis.

Bormann F, Rodríguez-Paredes M, Lasitschka F, Edelmann D, Musch T, Benner A, Bergman Y, Dieter SM, Ball CR, Glimm H, Linhart HG, Lyko F. Bormann F, et al. Among authors: linhart hg. Cell Rep. 2018 Jun 12;23(11):3407-3418. doi: 10.1016/j.celrep.2018.05.045. Cell Rep. 2018. PMID: 29898408 Free article.

10

C/EBPalpha is required for differentiation of white, but not brown, adipose tissue.

Linhart HG, Ishimura-Oka K, DeMayo F, Kibe T, Repka D, Poindexter B, Bick RJ, Darlington GJ. Linhart HG, et al. Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12532-7. doi: 10.1073/pnas.211416898. Epub 2001 Oct 16. Proc Natl Acad Sci U S A. 2001. PMID: 11606718 Free PMC article.

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