Kahan BD - Search Results

1

The Mannich base NC1153 promotes long-term allograft survival and spares the recipient from multiple toxicities.

Stepkowski SM, Kao J, Wang ME, Tejpal N, Podder H, Furian L, Dimmock J, Jha A, Das U, Kahan BD, Kirken RA. Stepkowski SM, et al. Among authors: kahan bd. J Immunol. 2005 Oct 1;175(7):4236-46. doi: 10.4049/jimmunol.175.7.4236. J Immunol. 2005. PMID: 16177063

2

Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin.

Stepkowski SM, Erwin-Cohen RA, Behbod F, Wang ME, Qu X, Tejpal N, Nagy ZS, Kahan BD, Kirken RA. Stepkowski SM, et al. Among authors: kahan bd. Blood. 2002 Jan 15;99(2):680-9. doi: 10.1182/blood.v99.2.680. Blood. 2002. PMID: 11781254 Free article.

3

Janus kinase 3: a novel target for selective transplant immunosupression.

Podder H, Kahan BD. Podder H, et al. Among authors: kahan bd. Expert Opin Ther Targets. 2004 Dec;8(6):613-29. doi: 10.1517/14728222.8.6.613. Expert Opin Ther Targets. 2004. PMID: 15584866

4

Allograft rejection requires STAT5a/b-regulated antiapoptotic activity in T cells but not B cells.

Zhang Y, Kirken RA, Furian L, Janczewska S, Qu X, Hancock WW, Wang M, Tejpal N, Kerman R, Kahan BD, Stepkowski SM. Zhang Y, et al. Among authors: kahan bd. J Immunol. 2006 Jan 1;176(1):128-37. doi: 10.4049/jimmunol.176.1.128. J Immunol. 2006. PMID: 16365403

5

Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats.

Ferraresso M, Tian L, Ghobrial R, Stepkowski SM, Kahan BD. Ferraresso M, et al. Among authors: kahan bd. J Immunol. 1994 Oct 1;153(7):3307-18. J Immunol. 1994. PMID: 8089500

6

Concomitant inhibition of Janus kinase 3 and calcineurin-dependent signaling pathways synergistically prolongs the survival of rat heart allografts.

Behbod F, Erwin-Cohen RA, Wang ME, Trawick BW, Qu X, Verani R, Kahan BD, Stepkowski SM, Kirken RA. Behbod F, et al. Among authors: kahan bd. J Immunol. 2001 Mar 15;166(6):3724-32. doi: 10.4049/jimmunol.166.6.3724. J Immunol. 2001. PMID: 11238613

7

Synergistic mechanisms by which sirolimus and cyclosporin inhibit rat heart and kidney allograft rejection.

Stepkowski SM, Tian L, Napoli KL, Ghobrial R, Wang ME, Chou TC, Kahan BD. Stepkowski SM, et al. Among authors: kahan bd. Clin Exp Immunol. 1997 Apr;108(1):63-8. doi: 10.1046/j.1365-2249.1997.d01-984.x. Clin Exp Immunol. 1997. PMID: 9097913 Free PMC article.

8

Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations.

Podder H, Stepkowski SM, Napoli KL, Clark J, Verani RR, Chou TC, Kahan BD. Podder H, et al. Among authors: kahan bd. J Am Soc Nephrol. 2001 May;12(5):1059-1071. doi: 10.1681/ASN.V1251059. J Am Soc Nephrol. 2001. PMID: 11316866

9

Allochimeric class I MHC protein-induced tolerance by partial TCR engagement requires activation of both CTL4- and common gamma-chain-dependent cytokine signals.

Stepkowski SM, Kirken RA, Trawick BW, Wang M, Tejpal N, Wang ME, Tian L, Clark J, Kahan BD. Stepkowski SM, et al. Among authors: kahan bd. Transplantation. 2002 Apr 27;73(8):1227-35. doi: 10.1097/00007890-200204270-00007. Transplantation. 2002. PMID: 11981413

10

Selection of lowly immunogenic and highly tolerogenic donor and recipient allochimeric class I major histocompatibility complex proteins.

Perez J, Stepkowski SM, Song P, Trawick B, Wang ME, Janczewska S, Kahan BD. Perez J, et al. Among authors: kahan bd. Transplantation. 2003 Oct 27;76(8):1201-7. doi: 10.1097/01.TP.0000082544.46595.F7. Transplantation. 2003. PMID: 14578754

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